HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: FLNC (Q8VHX6)
Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filamin~Integrin_b_cyt
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 787 Mm			1 2726
+	Mm
		515676 ITB2_MOUSE (24-785): 0: 625: 38.45		FLNC_MOUSE (1-2726): 0: 2985: 100.00
+	Mm
		222557 ITB3_MOUSE (1-787): 0: 793: 100.00		FLNA_MOUSE (148-2726): 0: 1496: 35.35
+	Hs
		396566 ITB3_HUMAN (1-787): 0: 763: 90.61		FLNA_HUMAN (148-2726): 0: 1495: 35.35
+	Mm
		222550 ITB3_MOUSE (1-787): 0: 793: 100.00		FLNB_MOUSE (147-2726): 0: 1450: 35.21
+	Mm
		447108 ITB1_MOUSE (10-786): 0: 733: 43.27		FLNA_MOUSE (148-2726): 0: 1496: 35.35
+	Hs
		403783 ITB1_HUMAN (10-786): 0: 728: 43.52		FLNA_HUMAN (148-2726): 0: 1495: 35.35
+	Hs
		261179 ITB3_HUMAN (1-787): 0: 763: 90.61		FLNB_HUMAN (147-2726): 0: 1449: 35.33
+	Hs
		577567 ITB6_HUMAN (30-785): 0: 692: 49.87		FLNA_HUMAN (148-2726): 0: 1495: 35.35
+	Hs
		261181 ITB1_HUMAN (10-786): 0: 728: 43.52		FLNB_HUMAN (147-2726): 0: 1449: 35.33
+	Hs
		261196 ITB6_HUMAN (30-785): 0: 692: 49.87		FLNB_HUMAN (147-2726): 0: 1449: 35.33
+	Hs
		597965 ITB7_HUMAN (31-785): 0: 637: 38.82		FLNA_HUMAN (148-2726): 0: 1495: 35.35
+	Mm
		515666 ITB2_MOUSE (24-785): 0: 625: 38.45		FLNA_MOUSE (148-2726): 0: 1496: 35.35
+	Hs
		556411 ITB4_HUMAN (5-717): 0: 615: 34.35		FLNA_HUMAN (148-2726): 0: 1495: 35.35
+	Mm
		515662 ITB2_MOUSE (24-785): 0: 625: 38.45		FLNB_MOUSE (147-2726): 0: 1450: 35.21
+	Mm
		222535 ITB3_MOUSE (1-787): 0: 793: 100.00		SPTB2_MOUSE (4-440): 5.7e-125: 444: 24.95
+	Gg
		396530 ITB1_CHICK (8-786): 0: 729: 43.23		ACTN1_CHICK (7-438): 7.68e-122: 411: 24.83
+	Hs
		403752 ITB1_HUMAN (10-786): 0: 728: 43.52		ACTN1_HUMAN (6-438): 9.31e-122: 411: 24.56
+	Rn
		88558 ITB1_RAT (10-786): 0: 726: 43.09		D3ZCV0_RAT (21-376): 3.76e-113: 385: 27.88
+	Mm
		447075 ITB1_MOUSE (10-786): 0: 733: 43.27		ACTN4_MOUSE (33-359): 1.38e-101: 352: 28.02
+	Mm
		515654 ITB2_MOUSE (24-785): 0: 625: 38.45		SPTB2_MOUSE (4-440): 5.7e-125: 444: 24.95