HitPredict

Interactor 1: FIMB (O59945)
Fimbrin
Gene: fim1

Interactor 2: ACT (P10989)
Actin (EC 3.6.4.-)
Gene: act1

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	28282023, 19713940
Identification Methods	pull down, cosedimentation in solution
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005884 - actin filament GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0032153 - cell division site GO:0120106 - mitotic actomyosin contractile ring, distal actin filament layer
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 614 Sp			1 375
+	Sc
		696467 FIMB_YEAST (1-614): 0: 554: 61.47		ACT_YEAST (1-375): 0: 588: 89.60
+	Mm
		892209 PLST_MOUSE (7-613): 0: 530: 38.55		ACTB_MOUSE (1-375): 0: 598: 90.40
+	Hs
		533285 PLST_HUMAN (7-613): 0: 529: 38.39		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		533292 PLST_HUMAN (7-613): 0: 529: 38.39		ACTG_HUMAN (1-375): 0: 598: 91.47
+	Hs
		533293 PLST_HUMAN (7-613): 0: 529: 38.39		ACTC_HUMAN (2-375): 0: 588: 89.04
+	Hs
		891766 PLSI_HUMAN (6-613): 8.6e-177: 517: 39.34		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		533207 PLSL_HUMAN (12-613): 1.98e-176: 516: 39.33		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		533209 PLSL_HUMAN (12-613): 1.98e-176: 516: 39.33		ACTG_HUMAN (1-375): 0: 598: 91.47
+	Hs
		932155 PLSI_HUMAN (6-613): 8.6e-177: 517: 39.34		ACTC_HUMAN (2-375): 0: 588: 89.04
+	Hs
		533210 PLSL_HUMAN (12-613): 1.98e-176: 516: 39.33		ACTC_HUMAN (2-375): 0: 588: 89.04
+	Hs
		929869 PLEC_HUMAN (107-387): 3.56e-84: 290: 16.84		ACTG_HUMAN (1-375): 0: 598: 91.47
+	Hs
		932171 PLEC_HUMAN (107-387): 3.56e-84: 290: 16.84		ACTC_HUMAN (2-375): 0: 588: 89.04
+	Hs
		892113 MACF1_HUMAN (369-613): 5.55e-80: 278: 23.29		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		891706 DYST_HUMAN (108-367): 4.75e-79: 275: 18.70		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		164588 SPTN2_HUMAN (372-612): 2.05e-77: 270: 21.86		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		932113 DYST_HUMAN (108-367): 4.75e-79: 275: 18.70		ACTC_HUMAN (2-375): 0: 588: 89.04
+	Hs
		506816 SPTB1_HUMAN (372-612): 1.58e-75: 264: 21.46		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		891697 SPTB2_HUMAN (372-612): 1.09e-74: 262: 21.05		ACTB_HUMAN (1-375): 0: 598: 90.40
+	Hs
		929824 SPTB2_HUMAN (372-612): 1.09e-74: 262: 21.05		ACTG_HUMAN (1-375): 0: 598: 91.47
+	Oc
		933099 Q07931_RABIT (372-612): 2.52e-85: 270: 18.62		ACTS_RABIT (2-375): 0: 588: 89.04