Protein: HXA5
Homeobox protein Hox-A5 (Homeobox protein Hox-1C)

Gene: HXA5, HOXA5
Organism: Homo sapiens
Interactions: 94
UniProt ID: P20719

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003016 - respiratory system process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

634830

PBX2
Pre-B-cell leukemia transcription factor 2

2

20

High-throughput

0.783

High

634846

TWST1
Twist-related protein 1

1

16

Small-scale

0.740

High

478282

HXD4
Homeobox protein Hox-D4

1

16

High-throughput

0.691

High

484815

HXB7
Homeobox protein Hox-B7

1

18

High-throughput

0.691

High

634876

TBX5
T-box transcription factor TBX5

1

20

High-throughput

0.618

High

634852

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

4

Small-scale

0.611

High

634837

CTBP2
C-terminal-binding protein 2

2

7

High-throughput

0.606

High

634863

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

6

High-throughput

0.606

High

634895

FOXA2
Hepatocyte nuclear factor 3-beta

2

20

Small-scale

0.602

High

274094

ANR17
Ankyrin repeat domain-containing protein 17

2

20

High-throughput

0.601

High

634865

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

9

High-throughput

0.601

High

634874

ERBIN
Erbin

2

6

High-throughput

0.601

High

634834

SOX2
Transcription factor SOX-2

2

20

High-throughput

0.584

High

634887

PICK1
PRKCA-binding protein

2

1

High-throughput

0.553

High

291212

NU155
Nuclear pore complex protein Nup155

2

1

High-throughput

0.549

High

634847

SMAD1
Mothers against decapentaplegic homolog 1

1

9

High-throughput

0.541

High

634886

ZN408
Zinc finger protein 408

1

5

High-throughput

0.541

High

634894

TF2AY
TFIIA-alpha and beta-like factor

1

3

High-throughput

0.541

High

302747

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.536

High

562556

RINI
Ribonuclease inhibitor

1

7

High-throughput

0.536

High

634823

S100P
Protein S100-P

1

12

High-throughput

0.536

High

634850

SDE2
Splicing regulator SDE2

1

2

High-throughput

0.536

High

634889

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

9

High-throughput

0.536

High

634827

DDIT3
DNA damage-inducible transcript 3 protein

1

0

High-throughput

0.518

High

634831

HD
Huntingtin

1

1

High-throughput

0.515

High

634870

ANM6
Protein arginine N-methyltransferase 6

1

5

High-throughput

0.508

High

634841

FOXO1
Forkhead box protein O1

1

20

Small-scale

0.501

High

634893

DNM3L
DNA

1

2

Small-scale

0.501

High

339652

KLF8
Krueppel-like factor 8

1

6

High-throughput

0.500

High

634862

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

229951

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

5

High-throughput

0.489

High

634857

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

20

High-throughput

0.489

High

634866

HBAP1
HSPB1-associated protein 1

1

3

High-throughput

0.489

High

634868

TRI11
E3 ubiquitin-protein ligase TRIM11

1

9

High-throughput

0.489

High

634869

SAHH3
Adenosylhomocysteinase 3

1

5

High-throughput

0.489

High

634871

BTBD9
BTB/POZ domain-containing protein 9

1

6

High-throughput

0.489

High

634884

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

8

High-throughput

0.489

High

142831

NFIB
Nuclear factor 1 B-type

1

17

High-throughput

0.479

High

211268

RFOX2
RNA binding protein fox-1 homolog 2

1

3

High-throughput

0.479

High

280500

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.479

High

315110

RECQ4
ATP-dependent DNA helicase Q4

1

9

High-throughput

0.479

High

473784

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

634828

VGFR3
Vascular endothelial growth factor receptor 3

1

3

High-throughput

0.479

High

634829

COIL
Coilin

1

1

High-throughput

0.479

High

634832

GATA4
Transcription factor GATA-4

1

10

High-throughput

0.479

High

634835

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.479

High

634842

NFIA
Nuclear factor 1 A-type

1

19

High-throughput

0.479

High

634844

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

10

High-throughput

0.479

High

634845

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

634848

EZH2
Histone-lysine N-methyltransferase EZH2

1

10

Small-scale

0.479

High

634849

MK14
Mitogen-activated protein kinase 14

1

8

High-throughput

0.479

High

634856

DDX42
ATP-dependent RNA helicase DDX42

1

2

High-throughput

0.479

High

634858

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.479

High

634860

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

634861

KAT6A
Histone acetyltransferase KAT6A

1

14

High-throughput

0.479

High

634864

ZN707
Zinc finger protein 707

1

5

High-throughput

0.479

High

634872

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.479

High

634873

CIC
Protein capicua homolog

1

18

High-throughput

0.479

High

634881

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.479

High

634885

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

634890

DDX56
Probable ATP-dependent RNA helicase DDX56

1

4

High-throughput

0.479

High

634891

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

634892

KDM5B
Lysine-specific demethylase 5B

1

6

Small-scale

0.479

High

634839

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.458

High

634853

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

634854

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

634859

FA98A
Protein FAM98A

1

0

High-throughput

0.458

High

634867

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

634883

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

634896

CARD8
Caspase recruitment domain-containing protein 8

1

0

High-throughput

0.458

High

634825

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

634826

MERL
Merlin

1

2

High-throughput

0.445

High

634880

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

3

High-throughput

0.445

High

164250

NRP1
Neuropilin-1

1

2

High-throughput

0.437

High

217382

E41L2
Band 4.1-like protein 2

1

1

High-throughput

0.437

High

343673

GGPPS
Geranylgeranyl pyrophosphate synthase

1

1

High-throughput

0.437

High

627500

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

3

High-throughput

0.437

High

634840

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

634843

SRC8
Src substrate cortactin

1

3

High-throughput

0.437

High

634888

DCA13
DDB1- and CUL4-associated factor 13

1

1

High-throughput

0.437

High

634851

ATAD2
ATPase family AAA domain-containing protein 2

1

0

High-throughput

0.426

High

97223

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

116501

H7C0V5
ANKHD1-EIF4EBP3 readthrough

1

20

High-throughput

0.407

High

634877

ERP44
Endoplasmic reticulum resident protein 44

2

0

High-throughput

0.328

High

223796

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.279

Low

634855

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

634882

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

634824

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

634833

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.249

Low

634836

RBM25
RNA-binding protein 25

1

0

High-throughput

0.249

Low

634838

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.249

Low

634875

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.249

Low

634878

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

634879

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025