HitPredict

Interactor 1: 3BP5 (O60239)
SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK)
Gene: SH3BP5

Interactor 2: RB11A (P62491)
Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (YL8)
Gene: RAB11A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	28514442, 34079125, 33961781, 34128958
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~SH3BP5
Common GO terms	GO:0030659 - cytoplasmic vesicle membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 216
+	Hs
		225240 3BP5_HUMAN (1-455): 0: 617: 100.00		RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37
+	Dm
		185693 3BP5H_DROME (37-286): 2.01e-102: 315: 48.22		O18335_DROME (1-214): 1.21e-88: 261: 85.51
+	Hs
		914164 3BP5L_HUMAN (18-284): 9.93e-92: 285: 43.07		RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00
+	Hs
		1079930 3BP5L_HUMAN (18-284): 9.93e-92: 285: 43.07		RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37
+	Hs
		884522 3BP5L_HUMAN (18-284): 9.93e-92: 285: 43.07		RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20
+	Ce
		136856 REI1_CAEEL (45-261): 7.65e-77: 241: 23.50		RB11A_CAEEL (1-213): 1.13e-85: 254: 80.28