HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: SCAF4 (O95104)
SR-related and CTD-associated factor 4 (CTD-binding SR-like protein RA4) (Splicing factor, arginine/serine-rich 15)
Gene: SCAF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 1147
+	Hs
		123816 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		SCAF4_HUMAN (1-1147): 1.83e-128: 423: 100.00
+	Hs
		304587 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		SCAF4_HUMAN (1-1147): 1.83e-128: 423: 100.00
+	Hs
		847124 CABIN_HUMAN (969-1229): 1.65e-25: 117: 15.39		SMCA4_HUMAN (629-1077): 2.71e-38: 158: 12.63
+	Hs
		847041 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		SMCA4_HUMAN (629-1077): 2.71e-38: 158: 12.63
+	Hs
		624816 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		SMCA4_HUMAN (629-1077): 2.71e-38: 158: 12.63
+	Hs
		554259 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		MUC1_HUMAN (438-1146): 2.57e-26: 119: 11.67
+	Mm
		444976 RPB1_MOUSE (1059-1159): 6.56e-09: 62.9: 23.30		DIDO1_MOUSE (604-1068): 3.3e-26: 119: 19.28
+	Mm
		1351630 PCLO_MOUSE (848-1405): 4.06e-11: 70.3: 12.13		PCLO_MOUSE (253-1061): 7.48e-20: 98.8: 9.17
+	Hs
		846837 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		SMCA2_HUMAN (671-1082): 2.33e-13: 77.2: 12.59
+	Dm
		113976 M9PB30_DROME (896-1454): 4.15e-11: 70.3: 9.90		M9PB30_DROME (129-545): 5.97e-14: 79.5: 10.70
+	Hs
		624815 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		SMCA2_HUMAN (671-1082): 2.33e-13: 77.2: 12.59
+	Hs
		297843 SC24D_HUMAN (986-1164): 5.57e-10: 66.4: 18.79		SC31A_HUMAN (553-883): 6.95e-11: 68.9: 13.06
+	Hs
		124109 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		CHD7_HUMAN (214-767): 2.67e-09: 63.9: 15.04
+	Mm
		444961 RPB1_MOUSE (1059-1159): 6.56e-09: 62.9: 23.30		SMCA4_MOUSE (717-1063): 1.45e-09: 64.9: 12.18