Interactor 1: SOX15 (O60248)
Transcription factor SOX-15 (Protein SOX-12) (Protein SOX-20) (SRY-box transcription factor 15)
Gene: SOX15

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 35140242
Identification Methods affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 9 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 233
Hs

1 393
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024