HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: KBL (O75600)
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)
Gene: GCAT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 419
+	Hs
		174181 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTC2_HUMAN (8-417): 7.58e-133: 394: 30.07
+	Hs
		226391 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HEM1_HUMAN (12-417): 6.68e-104: 322: 28.78
+	Hs
		174023 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTC1_HUMAN (18-415): 5.03e-102: 312: 24.02
+	Hs
		226662 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		GLYM_HUMAN (6-410): 2.65e-79: 255: 14.72
+	Hs
		270906 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KBL_HUMAN (1-419): 8.74e-139: 404: 100.00
+	At
		1091933 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GLYP3_ARATH (12-413): 7.7e-83: 265: 14.86
+	At
		1092415 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GLYM1_ARATH (5-412): 1.23e-81: 261: 14.07
+	At
		1091677 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GSA2_ARATH (18-411): 3.66e-62: 209: 17.30
+	At
		791089 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GSA1_ARATH (18-411): 3.24e-57: 196: 17.52