HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ACL6B (O94805)
Actin-like protein 6B (53 kDa BRG1-associated factor B) (Actin-related protein Baf53b) (ArpNalpha) (BRG1-associated factor 53B) (BAF53B)
Gene: ACTL6B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 426
+	Hs
		226187 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACL6A_HUMAN (1-426): 0: 777: 83.92
+	Hs
		312437 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ACL6A_HUMAN (1-426): 0: 777: 83.92
+	Hs
		227018 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTB_HUMAN (9-425): 0: 549: 35.49
+	Hs
		227123 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTG_HUMAN (9-425): 0: 549: 35.49
+	Hs
		227128 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTC_HUMAN (5-425): 0: 543: 36.11
+	Hs
		227131 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTS_HUMAN (5-425): 0: 543: 36.11
+	Hs
		227086 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTA_HUMAN (9-425): 0: 540: 35.73
+	Mm
		892218 PRKN_MOUSE (1-465): 6.53e-131: 388: 83.66		ACTB_MOUSE (9-425): 0: 549: 35.49
+	Mm
		933097 PRKN_MOUSE (1-465): 6.53e-131: 388: 83.66		ACTS_MOUSE (5-425): 0: 543: 36.11
+	Hs
		331432 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ACL6A_HUMAN (1-426): 0: 777: 83.92
+	Hs
		932245 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		ACTC_HUMAN (5-425): 0: 543: 36.11
+	Hs
		475544 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ACTB_HUMAN (9-425): 0: 549: 35.49
+	Hs
		475603 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ACTC_HUMAN (5-425): 0: 543: 36.11
+	Hs
		475605 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ACTS_HUMAN (5-425): 0: 543: 36.11
+	Zm
		24703 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		B4F989_MAIZE (5-425): 0: 541: 34.68
+	Sc
		477407 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		ACT_YEAST (10-425): 4.96e-82: 258: 37.08