Protein: RGPA1
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)

Gene: RGPA1, RALGAPA1
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q6GYQ0

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0046982 - protein heterodimerization activity
GO:0051056 - regulation of small GTPase mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1233144

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

3

14

High-throughput

0.855

High

978086

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

976340

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.675

High

1233143

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

4

2

High-throughput

0.630

High

126653

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

374681

RASH
GTPase HRas

1

12

High-throughput

0.618

High

375617

RASK
GTPase KRas

1

14

High-throughput

0.618

High

955292

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

956342

RAB2A
Ras-related protein Rab-2A

1

5

High-throughput

0.618

High

962161

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

988447

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015524

RHOG
Rho-related GTP-binding protein RhoG

1

18

High-throughput

0.618

High

1151740

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1233128

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

990353

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1233133

AP2M1
AP-2 complex subunit mu

3

1

High-throughput

0.609

High

540502

LAMP1
Lysosome-associated membrane glycoprotein 1

2

10

High-throughput

0.584

High

641614

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

6

High-throughput

0.576

High

372293

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.571

High

989008

AP2B1
AP-2 complex subunit beta

2

2

High-throughput

0.558

High

341085

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.553

High

601333

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

630843

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.553

High

901308

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.553

High

901878

RAB9A
Ras-related protein Rab-9A

1

9

High-throughput

0.553

High

953508

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.553

High

962768

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.553

High

1144960

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.553

High

1233131

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.553

High

1233142

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1159935

MEA1
Male-enhanced antigen 1

1

1

High-throughput

0.536

High

1233137

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

1

High-throughput

0.536

High

1233132

DLG3
Disks large homolog 3

1

5

High-throughput

0.489

High

241997

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

331052

KI20A
Kinesin-like protein KIF20A

1

8

High-throughput

0.479

High

580648

AMPN
Aminopeptidase N

1

1

High-throughput

0.479

High

608635

DDX5
Probable ATP-dependent RNA helicase DDX5

1

2

High-throughput

0.479

High

637569

FLNA
Filamin-A

1

1

High-throughput

0.479

High

691125

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

729944

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

730672

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

928474

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.479

High

966467

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

971644

1433E
14-3-3 protein epsilon

1

9

High-throughput

0.479

High

1041121

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1045404

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1049420

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1115728

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.479

High

1135341

SLMAP
Sarcolemmal membrane-associated protein

1

5

High-throughput

0.479

High

1149907

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

1233127

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1233139

DUS23
Dual specificity protein phosphatase 23

1

3

High-throughput

0.479

High

1233145

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1233130

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1130302

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

Small-scale

0.445

High

1233129

RLGPB
Ral GTPase-activating protein subunit beta

1

1

Small-scale

0.445

High

533689

CLUS
Clusterin

1

0

High-throughput

0.438

High

1233134

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

106107

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

189635

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

226078

STX6
Syntaxin-6

1

1

High-throughput

0.437

High

560424

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.437

High

562137

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

High-throughput

0.437

High

642931

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

1031418

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.437

High

1159692

OCLN
Occludin

1

3

High-throughput

0.437

High

1233125

STYK1
Tyrosine-protein kinase STYK1

1

5

High-throughput

0.437

High

1233126

LMTK1
Serine/threonine-protein kinase LMTK1

1

6

High-throughput

0.437

High

1233136

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.437

High

1233138

WDR83
WD repeat domain-containing protein 83

1

4

High-throughput

0.437

High

1233141

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.437

High

1233146

LAMP3
Lysosome-associated membrane glycoprotein 3

1

10

High-throughput

0.437

High

1233135

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

566709

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.269

Low

693000

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

880581

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1233140

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025