HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35256949, 24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 372
+	Hs
		227125 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		312470 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00
+	Hs
		312564 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		475940 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39
+	Hs
		475602 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89