HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1338
+	Hs
		226440 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PGFRA_HUMAN (11-666): 1.05e-59: 226: 19.41
+	Hs
		226529 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78
+	Hs
		452334 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73
+	Bt
		94412 UBC_BOVIN (1-149): 6.08e-49: 179: 19.33		F1MWF1_BOVIN (2-423): 4.8e-45: 180: 12.32
+	Hs
		475421 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		VGFR2_HUMAN (2-438): 9.05e-45: 179: 12.15
+	Hs
		475283 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14
+	Hs
		475426 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57