Protein: MSH3
DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)

Gene: MSH3
Organism: Homo sapiens
Interactions: 87
UniProt ID: P20585

Gene Ontology (top 5):
GO:0003690 - double-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594174

MSH2
DNA mismatch repair protein Msh2

12

13

Small-scale

0.984

High

594172

MLH1
DNA mismatch repair protein Mlh1

5

20

Small-scale

0.928

High

517045

PCNA
Proliferating cell nuclear antigen

6

6

Small-scale

0.737

High

594202

SLX4
Structure-specific endonuclease subunit SLX4

4

4

Small-scale

0.691

High

551929

RFA2
Replication protein A 32 kDa subunit

3

5

Small-scale

0.656

High

594168

RFA1
Replication protein A 70 kDa DNA-binding subunit

3

5

Small-scale

0.646

High

594184

H31
Histone H3.1

3

10

High-throughput

0.640

High

594176

PMS2
Mismatch repair endonuclease PMS2

1

20

High-throughput

0.618

High

594189

RFA4
Replication protein A 30 kDa subunit

2

5

Small-scale

0.611

High

345909

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.611

High

594166

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

594201

APLF
Aprataxin and PNK-like factor

2

0

High-throughput

0.602

High

594218

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.602

High

594227

EXO1
Exonuclease 1

2

6

Small-scale

0.595

High

594169

RFA3
Replication protein A 14 kDa subunit

2

2

High-throughput

0.584

High

594182

H4
Histone H4

2

2

High-throughput

0.584

High

594215

WDR76
WD repeat-containing protein 76

2

6

High-throughput

0.584

High

594219

MCM9
DNA helicase MCM9

2

4

Small-scale

0.584

High

594170

BRCA1
Breast cancer type 1 susceptibility protein

2

7

Small-scale

0.571

High

238253

RAD1
Cell cycle checkpoint protein RAD1

1

2

Small-scale

0.561

High

245877

HUS1
Checkpoint protein HUS1

1

2

Small-scale

0.561

High

594209

RAD9A
Cell cycle checkpoint control protein RAD9A

1

2

Small-scale

0.561

High

391544

H2A1B
Histone H2A type 1-B/E

1

4

High-throughput

0.536

High

594177

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.536

High

594179

MTPN
Myotrophin

1

3

High-throughput

0.536

High

594180

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.536

High

594230

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.536

High

507365

ERG
Transcriptional regulator ERG

1

0

High-throughput

0.518

High

594187

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.515

High

594204

H2B1H
Histone H2B type 1-H

1

9

High-throughput

0.515

High

594225

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.515

High

594188

EMX2
Homeobox protein EMX2

1

0

High-throughput

0.513

High

594195

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

0

High-throughput

0.513

High

594229

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

594165

XPA
DNA repair protein complementing XP-A cells

1

2

Small-scale

0.501

High

594181

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.501

High

594210

BARD1
BRCA1-associated RING domain protein 1

1

3

Small-scale

0.501

High

177819

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

233213

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

243923

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

322176

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

328731

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

384247

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

429823

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

455083

PARP1
Poly [ADP-ribose] polymerase 1

1

6

High-throughput

0.479

High

525843

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

569169

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

594171

COIL
Coilin

1

2

High-throughput

0.479

High

594173

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

594175

CENPA
Histone H3-like centromeric protein A

1

10

High-throughput

0.479

High

594178

KLF3
Krueppel-like factor 3

1

1

High-throughput

0.479

High

594183

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.479

High

594185

H33
Histone H3.3

1

10

High-throughput

0.479

High

594190

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

594191

ATR
Serine/threonine-protein kinase ATR

1

6

Small-scale

0.479

High

594194

BRD3
Bromodomain-containing protein 3

1

5

High-throughput

0.479

High

594198

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

594200

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.479

High

594205

SPDLY
Protein Spindly

1

1

High-throughput

0.479

High

594207

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

3

Small-scale

0.479

High

594212

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

594213

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

7

High-throughput

0.479

High

594220

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

594221

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

594222

HDAC6
Histone deacetylase 6

1

3

Small-scale

0.479

High

594224

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

594226

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

594228

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

594208

CTGE2
cTAGE family member 2

1

1

High-throughput

0.470

High

594206

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.460

High

456804

FURIN
Furin

1

0

High-throughput

0.458

High

594167

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

594197

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

594211

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

594223

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

256800

T22D2
TSC22 domain family protein 2

1

1

Small-scale

0.439

High

594186

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.437

High

594192

TRI29
Tripartite motif-containing protein 29

1

3

Small-scale

0.437

High

594193

CUL7
Cullin-7

1

1

High-throughput

0.437

High

594196

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

594199

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

594203

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

594214

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

594216

RHOF
Rho-related GTP-binding protein RhoF

1

2

High-throughput

0.437

High

486458

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

544937

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

594217

TLR9
Toll-like receptor 9

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024