HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24244333, 25959826
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 171
+	Hs
		159521 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37
+	Hs
		226583 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27
+	Zm
		6352 A0A1D6E7J6_MAIZE (225-456): 1.63e-71: 238: 21.89		A0A1D6K120_MAIZE (112-170): 2.76e-11: 60.9: 25.42
+	At
		1092417 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPKQ_ARATH (95-171): 9.07e-14: 69.9: 27.27
+	At
		1091633 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPK5_ARATH (95-171): 4.34e-13: 68: 25.97
+	At
		1091642 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPKB_ARATH (95-171): 8.73e-13: 66.8: 24.68