HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RBM25 (P49756)
RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)
Gene: RBM25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016607 - nuclear speck GO:0042981 - regulation of apoptotic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 843
+	Hs
		228104 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		BD1L1_HUMAN (166-744): 5.22e-24: 111: 12.59
+	Hs
		226679 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Hs
		226028 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ROCK2_HUMAN (55-790): 3.56e-18: 92.2: 9.38
+	Hs
		228645 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTFT_HUMAN (76-170): 1.7e-15: 82.5: 29.17
+	Hs
		226655 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTF2_HUMAN (78-259): 3.07e-15: 81.8: 16.84
+	Hs
		226436 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DESP_HUMAN (125-772): 9.93e-15: 81: 11.43
+	Hs
		226680 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MYH10_HUMAN (228-817): 4.57e-14: 78.7: 9.49
+	Hs
		227627 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		GRDN_HUMAN (116-772): 9.29e-12: 71.4: 11.87
+	Hs
		227506 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30
+	Hs
		228183 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DC2I1_HUMAN (173-595): 2.48e-10: 66.5: 15.79
+	Hs
		227833 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR87_HUMAN (170-657): 1.32e-09: 64.4: 9.53
+	Hs
		475417 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Hs
		476483 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ITSN2_HUMAN (3-678): 5.19e-14: 78.7: 10.77
+	Hs
		475789 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30
+	Hs
		475816 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ITSN1_HUMAN (394-779): 1.8e-11: 70.2: 12.34
+	At
		188090 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		U2A2A_ARATH (290-392): 5.6e-09: 61.6: 34.62