HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: AK17A (Q02040)
A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)
Gene: AKAP17A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 695
+	Hs
		227149 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAP1A_HUMAN (187-520): 1.4e-35: 147: 14.16
+	Hs
		227634 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HYDIN_HUMAN (243-633): 3.38e-24: 111: 12.25
+	Hs
		227833 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR87_HUMAN (158-654): 8.7e-23: 106: 14.23
+	Hs
		228398 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CFA57_HUMAN (210-448): 6.79e-10: 64.9: 12.70
+	Hs
		228316 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBC31_HUMAN (279-469): 8.63e-09: 61.1: 15.90
+	Hs
		475855 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		HYDIN_HUMAN (243-633): 3.38e-24: 111: 12.25
+	Hs
		476483 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ITSN2_HUMAN (226-666): 1.26e-21: 102: 14.03
+	Hs
		475816 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ITSN1_HUMAN (144-527): 9.89e-18: 90.1: 10.05