Protein: KRT81
Keratin, type II cuticular Hb1 (Hair keratin K2.9) (Keratin, hair, basic, 1) (Keratin-81) (K81) (Metastatic lymph node 137 gene protein) (MLN 137) (Type II hair keratin Hb1) (Type-II keratin Kb21) (ghHKb1) (ghHb1)

Gene: KRT81
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q14533

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization
GO:0045095 - keratin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

300755

KRT38
Keratin, type I cuticular Ha8

4

20

High-throughput

0.916

High

1127806

K1H1
Keratin, type I cuticular Ha1

4

20

High-throughput

0.904

High

1127811

K1C40
Keratin, type I cytoskeletal 40

3

20

High-throughput

0.871

High

618031

K1C15
Keratin, type I cytoskeletal 15

3

20

High-throughput

0.861

High

300653

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.794

High

300353

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

385104

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.783

High

436865

K1C18
Keratin, type I cytoskeletal 18

2

20

High-throughput

0.783

High

475576

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

476313

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

1127812

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.783

High

1127814

K1C28
Keratin, type I cytoskeletal 28

2

20

High-throughput

0.783

High

1127815

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

1127816

K1C26
Keratin, type I cytoskeletal 26

2

20

High-throughput

0.783

High

1127819

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

733128

OTX1
Homeobox protein OTX1

4

5

High-throughput

0.639

High

300571

KRT36
Keratin, type I cuticular Ha6

1

20

High-throughput

0.621

High

566266

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.621

High

1127644

KT33B
Keratin, type I cuticular Ha3-II

1

20

High-throughput

0.621

High

1127808

K1C24
Keratin, type I cytoskeletal 24

1

20

High-throughput

0.621

High

1127817

K1C25
Keratin, type I cytoskeletal 25

1

20

High-throughput

0.621

High

1127809

PKHG6
Pleckstrin homology domain-containing family G member 6

2

2

High-throughput

0.571

High

70204

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

217090

MS18B
Protein Mis18-beta

2

6

High-throughput

0.553

High

337216

LCA5L
Lebercilin-like protein

2

1

High-throughput

0.553

High

885243

HXA1
Homeobox protein Hox-A1

2

8

High-throughput

0.553

High

289999

OFD1
Centriole and centriolar satellite protein OFD1

1

3

High-throughput

0.536

High

702111

ITPI2
Protein ITPRID2

1

2

High-throughput

0.536

High

1127804

PLSI
Plastin-1

1

5

High-throughput

0.536

High

1127805

PCM1
Pericentriolar material 1 protein

1

4

High-throughput

0.536

High

1127821

EXOC4
Exocyst complex component 4

1

2

High-throughput

0.536

High

1127827

FA83D
Protein FAM83D

1

4

High-throughput

0.536

High

1127829

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

8

High-throughput

0.536

High

384412

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.515

High

1127820

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

1007560

PRAME
Melanoma antigen preferentially expressed in tumors

1

5

High-throughput

0.489

High

1068830

IFFO1
Non-homologous end joining factor IFFO1

1

20

High-throughput

0.489

High

1127807

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.489

High

1127810

PREP
Presequence protease, mitochondrial

1

4

High-throughput

0.489

High

1127822

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.489

High

389361

FINC
Fibronectin

1

6

High-throughput

0.479

High

425499

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.479

High

563767

CFTR
Cystic fibrosis transmembrane conductance regulator

1

16

High-throughput

0.479

High

590903

TIMP2
Metalloproteinase inhibitor 2

1

6

High-throughput

0.479

High

766195

NOS2
Nitric oxide synthase, inducible

1

1

High-throughput

0.479

High

934610

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

987642

GRB2
Growth factor receptor-bound protein 2

1

18

High-throughput

0.479

High

1127825

NECD
Necdin

1

4

High-throughput

0.479

High

1127828

MYO10
Unconventional myosin-X

1

3

Small-scale

0.479

High

1127813

Q6FHY5
MEOX2 protein

1

6

High-throughput

0.470

High

1127818

Q86V38
Atrophin 1

1

2

High-throughput

0.470

High

944802

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.460

High

1023779

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

6

High-throughput

0.445

High

893864

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.439

High

1127823

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

3

High-throughput

0.439

High

1127824

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

8

High-throughput

0.407

High

1127826

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.304

High

555482

SKIL
Ski-like protein

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025