HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: NSUN2 (Q08J23)
RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (Substrate of AIM1/Aurora kinase B) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) (tRNA methyltransferase 4 homolog) (hTrm4)
Gene: NSUN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 767
+	Hs
		312589 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		226783 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NOP2_HUMAN (22-533): 1.53e-126: 398: 20.04
+	Hs
		228403 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NSUN5_HUMAN (73-431): 8.5e-98: 311: 23.35
+	Hs
		228152 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NSUN6_HUMAN (122-433): 1.94e-79: 264: 26.58
+	Hs
		312510 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		NOP2_HUMAN (22-533): 1.53e-126: 398: 20.04
+	Hs
		1286625 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		NSUN4_HUMAN (91-337): 8.82e-58: 203: 25.10
+	Hs
		476172 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		NSUN4_HUMAN (91-337): 8.82e-58: 203: 25.10