HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 305
+	Hs
		226531 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		609949 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		226327 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		226923 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		228332 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (1-100): 1.45e-15: 78.9: 22.77
+	Hs
		227415 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161907 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		312478 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		453681 RNF14_HUMAN (161-464): 6.69e-69: 229: 21.56		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		312456 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		312523 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		312642 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		312603 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161924 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57