HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RCN2 (Q14257)
Reticulocalbin-2 (Calcium-binding protein ERC-55) (E6-binding protein) (E6BP)
Gene: RCN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 317
+	Hs
		216120 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CALU_HUMAN (1-313): 5.78e-60: 195: 35.51
+	Hs
		227516 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RCN1_HUMAN (31-317): 1.33e-49: 169: 37.98
+	Hs
		226583 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CALL3_HUMAN (219-316): 5.46e-15: 72.7: 20.41
+	Hs
		312604 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RCN2_HUMAN (1-317): 1.81e-55: 184: 100.00
+	Zm
		6352 A0A1D6E7J6_MAIZE (225-456): 1.63e-71: 238: 21.89		A0A1D6K120_MAIZE (25-180): 1.83e-10: 61.2: 14.65
+	At
		1091633 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPK5_ARATH (144-290): 8.11e-20: 91.7: 18.37
+	At
		1091642 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPKB_ARATH (144-289): 4.89e-19: 89: 19.86
+	At
		1092417 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CDPKQ_ARATH (213-316): 5.39e-18: 86.2: 16.35