HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: MICA3 (Q7RTP6)
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
Gene: MICAL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 2002
+	Hs
		211433 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTN4_HUMAN (434-1045): 2.63e-104: 359: 14.72
+	Hs
		226387 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTN1_HUMAN (434-1065): 1.24e-103: 357: 14.97
+	Hs
		227192 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		164537 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (690-1863): 8.82e-13: 76.7: 10.84
+	Hs
		227506 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PLEC_HUMAN (619-1989): 3.73e-11: 71.1: 10.87
+	Hs
		475789 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PLEC_HUMAN (619-1989): 3.73e-11: 71.1: 10.87