Protein: LIMS1
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)

Gene: LIMS1
Organism: Homo sapiens
Interactions: 86
UniProt ID: P48059

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

870124

ILK
Scaffold protein ILK

25

18

Small-scale

0.992

High

870129

RSU1
Ras suppressor protein 1

7

5

High-throughput

0.969

High

870172

PARVA
Alpha-parvin

5

10

Small-scale

0.919

High

870164

PARVG
Gamma-parvin

4

20

High-throughput

0.892

High

870131

TRIP6
Thyroid receptor-interacting protein 6

3

18

High-throughput

0.861

High

870165

PARVB
Beta-parvin

3

10

High-throughput

0.861

High

870115

PAXI
Paxillin

2

17

High-throughput

0.789

High

870147

LMO3
LIM domain only protein 3

2

19

High-throughput

0.783

High

253941

LPXN
Leupaxin

1

19

High-throughput

0.698

High

870116

CSRP3
Cysteine and glycine-rich protein 3

1

18

High-throughput

0.698

High

870155

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

10

High-throughput

0.698

High

222031

NCK2
Cytoplasmic protein NCK2

4

20

Small-scale

0.692

High

870118

DAPK1
Death-associated protein kinase 1

1

3

High-throughput

0.692

High

870142

ASPM
Abnormal spindle-like microcephaly-associated protein

1

15

High-throughput

0.691

High

870151

MY18A
Unconventional myosin-XVIIIa

3

8

High-throughput

0.667

High

870152

FERM2
Fermitin family homolog 2

1

5

Small-scale

0.647

High

416739

TYSY
Thymidylate synthase

3

0

High-throughput

0.638

High

870180

RBGP1
Rab GTPase-activating protein 1

3

0

High-throughput

0.638

High

870181

MYH4
Myosin-4

2

5

High-throughput

0.628

High

556903

MYH7
Myosin-7

2

5

High-throughput

0.611

High

870170

BMP2K
BMP-2-inducible protein kinase

2

8

High-throughput

0.611

High

694313

CO8A1
Collagen alpha-1(VIII) chain

2

1

High-throughput

0.606

High

870119

GEM
GTP-binding protein GEM

2

4

High-throughput

0.606

High

870130

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.606

High

870136

KPRP
Keratinocyte proline-rich protein

2

3

High-throughput

0.606

High

870140

ZN410
Zinc finger protein 410

2

11

High-throughput

0.606

High

870145

CTSR1
Cation channel sperm-associated protein 1

2

7

High-throughput

0.606

High

870148

ZN417
Zinc finger protein 417

2

9

High-throughput

0.606

High

870149

ZN564
Zinc finger protein 564

2

6

High-throughput

0.606

High

870156

ZN587
Zinc finger protein 587

2

9

High-throughput

0.606

High

870159

SCNM1
Sodium channel modifier 1

2

3

High-throughput

0.606

High

870173

ZIM2
Zinc finger imprinted 2

2

9

High-throughput

0.606

High

292335

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.580

High

870161

IN80B
INO80 complex subunit B

2

0

High-throughput

0.580

High

870139

URP2
Fermitin family homolog 3

1

5

Small-scale

0.579

High

371441

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.575

High

870166

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

9

Small-scale

0.561

High

870169

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.560

High

870158

CTIP
DNA endonuclease RBBP8

2

1

High-throughput

0.555

High

870134

C19L2
CWF19-like protein 2

2

1

High-throughput

0.553

High

870141

F90A1
Protein FAM90A1

2

2

High-throughput

0.553

High

870171

TB22B
TBC1 domain family member 22B

2

2

High-throughput

0.553

High

299523

TRIO
Triple functional domain protein

1

11

High-throughput

0.541

High

334711

IPO7
Importin-7

1

2

High-throughput

0.541

High

635500

NEBU
Nebulin

1

7

High-throughput

0.541

High

870117

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.541

High

870137

ZMYM4
Zinc finger MYM-type protein 4

1

11

High-throughput

0.541

High

870143

OSR2
Protein odd-skipped-related 2

1

8

High-throughput

0.541

High

870150

TITIN
Titin

1

13

High-throughput

0.541

High

870162

PEG3
Paternally-expressed gene 3 protein

1

4

High-throughput

0.541

High

870174

PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

1

1

High-throughput

0.541

High

870175

ATS9
A disintegrin and metalloproteinase with thrombospondin motifs 9

1

5

High-throughput

0.541

High

691670

MK03
Mitogen-activated protein kinase 3

1

6

High-throughput

0.536

High

870128

KIF22
Kinesin-like protein KIF22

1

2

High-throughput

0.536

High

870132

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

709287

CCN2
CCN family member 2

1

0

High-throughput

0.518

High

870122

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.518

High

870167

ZN160
Zinc finger protein 160

1

0

High-throughput

0.518

High

870176

ATX10
Ataxin-10

1

0

High-throughput

0.518

High

870154

MY15B
Unconventional myosin-XVB

1

10

High-throughput

0.515

High

559259

XRCC5
X-ray repair cross-complementing protein 5

1

0

High-throughput

0.513

High

870133

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

870135

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

241037

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

293359

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

529315

TAU
Microtubule-associated protein tau

1

9

Small-scale

0.479

High

629648

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

713945

PML
Protein PML

1

16

High-throughput

0.479

High

870120

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

16

High-throughput

0.479

High

870123

TIF1B
Transcription intermediary factor 1-beta

1

17

High-throughput

0.479

High

870126

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.479

High

870127

CUL3
Cullin-3

1

8

High-throughput

0.479

High

870138

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

870153

REPS1
RalBP1-associated Eps domain-containing protein 1

1

1

High-throughput

0.479

High

870157

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.479

High

870163

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.479

High

870177

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

870178

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.479

High

870125

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

870160

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.458

High

870168

PPA6
Lysophosphatidic acid phosphatase type 6

1

0

High-throughput

0.458

High

844734

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.445

High

870121

ACTB
Actin, cytoplasmic 1

1

12

Small-scale

0.445

High

870144

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

8

Small-scale

0.437

High

870179

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.426

High

870146

NEUA
N-acylneuraminate cytidylyltransferase

3

0

High-throughput

0.347

High


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Last updated: 11Aug2025