HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: FUBP1 (Q96AE4)
Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V)
Gene: FUBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16672220, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 644
+	Hs
		228262 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		228358 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FUBP3_HUMAN (168-629): 3.66e-31: 130: 18.94
+	Hs
		228921 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B1_HUMAN (86-271): 2.86e-25: 112: 22.46
+	Hs
		227521 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCBP2_HUMAN (21-353): 4.85e-23: 103: 15.78
+	Hs
		229223 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B2_HUMAN (255-561): 2.31e-17: 87.8: 14.38
+	Hs
		127952 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B3_HUMAN (260-573): 5.8e-14: 77: 14.11
+	Hs
		227520 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCBP1_HUMAN (7-173): 7.39e-14: 75.5: 20.24
+	Hs
		476143 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		1072089 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		PCBP1_HUMAN (7-173): 7.39e-14: 75.5: 20.24
+	Hs
		475796 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PCBP2_HUMAN (21-353): 4.85e-23: 103: 15.78
+	Hs
		128003 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		IF2B3_HUMAN (260-573): 5.8e-14: 77: 14.11