Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: VPS35 (Q96QK1)
Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)
Gene: VPS35

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.55 0.613

The method score is based on:

Property Details
Experiments 29893854, 35509820, 35256949
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
GO:0010629 - negative regulation of gene expression
GO:0010821 - regulation of mitochondrion organization
GO:0014069 - postsynaptic density
and 9 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024