HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ANM1 (Q99873)
Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4)
Gene: PRMT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0046329 - negative regulation of JNK cascade
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 371
+	Hs
		226006 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM3_HUMAN (24-363): 3.48e-136: 400: 46.96
+	Hs
		226986 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM2_HUMAN (36-364): 5.95e-130: 380: 32.74
+	Hs
		227951 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CARM1_HUMAN (12-361): 4.58e-117: 353: 32.80
+	Hs
		153503 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM5_HUMAN (4-342): 4.31e-98: 306: 16.53
+	Hs
		474972 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		ANM2_HUMAN (36-364): 5.95e-130: 380: 32.74
+	Hs
		153518 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ANM5_HUMAN (4-342): 4.31e-98: 306: 16.53
+	At
		1091739 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ANM13_ARATH (35-357): 1.94e-120: 360: 32.64
+	Hs
		153545 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ANM5_HUMAN (4-342): 4.31e-98: 306: 16.53
+	Hs
		476454 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ANM7_HUMAN (67-320): 1.28e-16: 83.1: 23.43