HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: STAU2 (Q9NUL3)
Double-stranded RNA-binding protein Staufen homolog 2
Gene: STAU2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0030544 - Hsp70 protein binding GO:0034599 - cellular response to oxidative stress GO:0043005 - neuron projection
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 570
+	Hs
		226065 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69
+	Hs
		226168 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33
+	Hs
		226490 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		E2AK2_HUMAN (10-212): 2.07e-26: 115: 21.46
+	Hs
		227305 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ILF3_HUMAN (274-428): 1.06e-11: 70: 21.38
+	Hs
		312436 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33
+	Hs
		474991 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		RED1_HUMAN (306-423): 3.65e-19: 93.5: 27.50
+	Hs
		312593 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ILF3_HUMAN (274-428): 1.06e-11: 70: 21.38
+	Hs
		475615 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RED1_HUMAN (306-423): 3.65e-19: 93.5: 27.50
+	Hs
		475682 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ILF3_HUMAN (274-428): 1.06e-11: 70: 21.38