Protein: ZW10
Centromere/kinetochore protein zw10 homolog

Gene: ZW10
Organism: Homo sapiens
Interactions: 204
UniProt ID: O43264

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000132 - establishment of mitotic spindle orientation
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199344

RINT1
RAD50-interacting protein 1

6

1

Small-scale

0.742

High

199411

STX18
Syntaxin-18

7

0

Small-scale

0.714

High

199301

KNTC1
Kinetochore-associated protein 1

4

3

Small-scale

0.694

High

58016

NBAS
NBAS subunit of NRZ tethering complex

4

1

Small-scale

0.687

High

199409

USE1
Vesicle transport protein USE1

4

0

Small-scale

0.667

High

199286

BASI
Basigin

3

1

High-throughput

0.667

High

199246

SC22B
Vesicle-trafficking protein SEC22b

3

0

High-throughput

0.646

High

199283

OPRM
Mu-type opioid receptor

2

2

High-throughput

0.628

High

199285

COPB2
Coatomer subunit beta'

2

1

Small-scale

0.618

High

199311

SNAA
Alpha-soluble NSF attachment protein

2

0

High-throughput

0.602

High

199325

SEC20
Vesicle transport protein SEC20

2

0

High-throughput

0.602

High

199397

ZWILC
Protein zwilch homolog

2

0

Small-scale

0.602

High

50055

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.576

High

199245

VAMP4
Vesicle-associated membrane protein 4

2

1

High-throughput

0.574

High

199251

VAMP5
Vesicle-associated membrane protein 5

2

2

High-throughput

0.574

High

199367

SCFD2
Sec1 family domain-containing protein 2

2

1

High-throughput

0.574

High

199362

DHB11
Estradiol 17-beta-dehydrogenase 11

2

2

High-throughput

0.571

High

199253

ZWINT
ZW10 interactor

2

0

Small-scale

0.563

High

199312

PAR2
Proteinase-activated receptor 2

2

4

High-throughput

0.558

High

199321

REEP5
Receptor expression-enhancing protein 5

2

0

High-throughput

0.547

High

199357

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

Small-scale

0.537

High

152117

STX16
Syntaxin-16

1

2

High-throughput

0.536

High

171887

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.536

High

199275

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.536

High

199309

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

199322

ACK1
Activated CDC42 kinase 1

1

1

High-throughput

0.536

High

199381

CML1
Chemerin-like receptor 1

1

4

High-throughput

0.536

High

123430

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.513

High

126733

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

149488

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

169323

BET1
BET1 homolog

1

0

High-throughput

0.513

High

196696

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

199241

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

199254

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.513

High

199269

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

199276

STOM
Stomatin

1

0

High-throughput

0.513

High

199291

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

199299

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

199310

MK10
Mitogen-activated protein kinase 10

1

0

High-throughput

0.513

High

199314

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.513

High

199320

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

199352

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

199358

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

199368

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.513

High

199373

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

199380

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

199390

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

199391

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

199405

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

199412

UVRAG
UV radiation resistance-associated gene protein

1

0

Small-scale

0.513

High

199417

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

199422

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

199263

INSR
Insulin receptor

1

2

High-throughput

0.500

High

199266

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

1

High-throughput

0.500

High

199287

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

199419

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

126561

P2Y10
Putative P2Y purinoceptor 10

1

5

High-throughput

0.489

High

199256

S1PR4
Sphingosine 1-phosphate receptor 4

1

2

High-throughput

0.489

High

199284

APJ
Apelin receptor

1

3

High-throughput

0.489

High

199306

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

199307

EFNA5
Ephrin-A5

1

1

High-throughput

0.489

High

199328

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.489

High

199426

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

154891

NDC80
Kinetochore protein NDC80 homolog

1

1

Small-scale

0.484

High

199262

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

199258

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

199271

RAC2
Ras-related C3 botulinum toxin substrate 2

1

1

High-throughput

0.479

High

199273

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

199302

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

199303

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

199315

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.479

High

199324

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

199327

STX3
Syntaxin-3

1

2

High-throughput

0.479

High

199340

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

1

High-throughput

0.479

High

199349

PTF1A
Pancreas transcription factor 1 subunit alpha

1

0

Small-scale

0.460

High

163671

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

199244

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.458

High

199248

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

199261

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

199272

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

199274

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

199277

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

199280

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

199289

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

199290

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

199294

PAXI
Paxillin

1

0

High-throughput

0.458

High

199295

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

199300

EMD
Emerin

1

0

High-throughput

0.458

High

199313

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

199323

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

199329

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

199338

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

199341

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

199343

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

199346

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

199350

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

199354

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

199370

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

199372

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

199376

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

199379

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

199386

DERL1
Derlin-1

1

0

High-throughput

0.458

High

199394

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

199396

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

199398

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.458

High

199407

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

199416

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

199423

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.458

High

48190

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

99755

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.445

High

199243

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

199252

RTN3
Reticulon-3

1

2

High-throughput

0.445

High

199255

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

199278

CALR
Calreticulin

1

1

High-throughput

0.445

High

199279

CALX
Calnexin

1

1

High-throughput

0.445

High

199298

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

199330

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.445

High

199336

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

199337

DHC24
Delta(24)-sterol reductase

1

1

High-throughput

0.445

High

199342

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.445

High

199355

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

199365

ATLA2
Atlastin-2

1

2

High-throughput

0.445

High

199369

ATLA1
Atlastin-1

1

2

High-throughput

0.445

High

199377

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

199384

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

199389

RGAP1
Rac GTPase-activating protein 1

1

1

High-throughput

0.445

High

199393

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

199400

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

199410

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

199413

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

199420

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.445

High

199421

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

199427

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

199260

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

199395

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

199239

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

199240

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

199247

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

199249

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

199250

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.426

High

199257

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

199264

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

199267

TAU
Microtubule-associated protein tau

1

0

Small-scale

0.426

High

199268

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

199270

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

199292

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

199293

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

199296

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

199304

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

199305

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

199308

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

199316

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

199317

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

199318

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

199319

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.426

High

199326

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

199331

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

199332

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

199333

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

199334

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

199335

RCN1
Reticulocalbin-1

1

0

High-throughput

0.426

High

199339

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

199345

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

199348

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.426

High

199359

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

199360

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

199363

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

199364

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

199366

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.426

High

199371

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

199375

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

199378

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

199383

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

199385

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

199387

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

199388

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

199392

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

199399

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.426

High

199401

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

199403

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.426

High

199404

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.426

High

199408

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

199425

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

199297

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

199265

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.328

High

199288

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

0

High-throughput

0.328

High

199415

CS025
UPF0449 protein C19orf25

2

0

Small-scale

0.328

High

199418

FZD10
Frizzled-10

2

0

High-throughput

0.328

High

199259

FINC
Fibronectin

1

0

High-throughput

0.279

Low

199281

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.279

Low

199353

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

199361

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.279

Low

199374

ULK4
Serine/threonine-protein kinase ULK4

1

0

High-throughput

0.279

Low

199414

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

199424

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.269

Low

199242

SCN2B
Sodium channel subunit beta-2

1

0

High-throughput

0.249

Low

199282

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

199347

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

199351

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

199356

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

199402

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

852

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

199382

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

199406

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024