HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RN112 (Q9ULX5)
RING finger protein 112 (EC 2.3.2.27) (Brain finger protein) (Zinc finger protein 179)
Gene: RNF112

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~zf-C3HC4
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0014069 - postsynaptic density
GO:0043005 - neuron projection
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024