HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: PSD13 (Q9UNM6)
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)
Gene: PSMD13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	35509820, 35987950, 35256949, 23503661
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 376
+	Hs
		476570 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PSD13_HUMAN (1-376): 5.33e-175: 493: 100.00
+	Hs
		227870 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		EIF3M_HUMAN (180-367): 2.2e-47: 166: 20.31
+	At
		1091760 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PS13B_ARATH (7-375): 1.26e-143: 414: 37.73
+	Sc
		477434 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		RPN9_YEAST (14-374): 3.08e-110: 329: 30.69
+	At
		1091815 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PS13A_ARATH (7-375): 5.37e-142: 410: 37.47
+	Hs
		475195 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		CSN7B_HUMAN (199-373): 8.34e-46: 159: 17.61
+	Hs
		476401 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CSN7B_HUMAN (199-373): 8.34e-46: 159: 17.61