Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: NLRP3 (Q96P20)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0016887 - ATP hydrolysis activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1052
Hs

1 1036
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024