HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: DNM3B (Q9UBC3)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB)
Gene: DNMT3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	15148359, 15120635
Identification Methods	biochemical, affinity chromatography technology, pull down
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1052 Hs			1 853
+	Hs
		1059917 CHD4_HUMAN (14-945): 0: 769: 26.95		DNM3B_HUMAN (1-853): 0: 1352: 100.00
+	Hs
		1336301 CHD8_HUMAN (6-1031): 0: 758: 26.13		DNM3B_HUMAN (1-853): 0: 1352: 100.00
+	Hs
		229463 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50
+	Hs
		658719 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50
+	Hs
		1255039 CHD5_HUMAN (5-1050): 0: 809: 26.28		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50
+	Hs
		1018645 CHD3_HUMAN (8-1052): 0: 801: 26.23		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50
+	Hs
		1059802 CHD4_HUMAN (14-945): 0: 769: 26.95		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50