HitPredict

Interactor 1: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1321 Hs			1 618
+	Hs
		229651 JIP4_HUMAN (1-1321): 0: 803: 100.00		RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34
+	Hs
		894827 JIP3_HUMAN (1-1321): 0: 731: 54.49		RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34
+	Hs
		164111 ARHGA_HUMAN (945-1270): 3.87e-78: 285: 21.58		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		164122 ARHGA_HUMAN (945-1270): 3.87e-78: 285: 21.58		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		164115 ARHGA_HUMAN (945-1270): 3.87e-78: 285: 21.58		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		900813 ARHGH_HUMAN (339-1316): 2.58e-130: 445: 18.21		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		164114 ARHGA_HUMAN (945-1270): 3.87e-78: 285: 21.58		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		164112 ARHGA_HUMAN (945-1270): 3.87e-78: 285: 21.58		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		254462 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		254472 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		254468 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		148551 CTRO_HUMAN (310-776): 4.58e-19: 96.1: 11.60		RAB13_HUMAN (5-180): 1.15e-72: 234: 20.23
+	Hs
		254466 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		254467 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		254464 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		254515 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		254433 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120238 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		254445 ROCK2_HUMAN (276-773): 8.13e-21: 101: 12.24		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26
+	Hs
		148297 CTRO_HUMAN (310-776): 4.58e-19: 96.1: 11.60		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25