HitPredict

Interactor 1: ZN292 (O60281)
Zinc finger protein 292
Gene: ZNF292

Interactor 2: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2723 Hs			1 191
+	Hs
		229796 ZN292_HUMAN (1-2723): 0: 2026: 98.90		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		229793 ZN292_HUMAN (1-2723): 0: 2026: 98.90		CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65
+	Hs
		203598 ZN292_HUMAN (1-2723): 0: 2026: 98.90		SUV91_HUMAN (4-135): 2.04e-36: 132: 19.70
+	Mm
		1322182 ZN292_MOUSE (1-2723): 0: 1824: 75.11		Q9DCC5_MOUSE (1-181): 3.06e-62: 192: 60.22
+	Hs
		64135 ZN729_HUMAN (355-1401): 0: 745: 11.89		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		64140 ZN729_HUMAN (355-1401): 0: 745: 11.89		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		64138 ZN729_HUMAN (355-1401): 0: 745: 11.89		CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65
+	Hs
		67424 ZN850_HUMAN (789-1412): 1.05e-112: 390: 11.51		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		983755 ZNF91_HUMAN (1712-2171): 1.1e-99: 353: 11.55		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		800409 ZN569_HUMAN (885-1414): 1.11e-80: 284: 10.71		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		800406 Z585B_HUMAN (909-1416): 1.48e-65: 241: 9.92		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		800425 Z585A_HUMAN (893-1416): 2.52e-65: 241: 8.98		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		549158 ZN250_HUMAN (592-873): 2.58e-70: 250: 15.39		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		1027128 ZN565_HUMAN (508-746): 2.15e-70: 249: 17.41		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		728565 ZNF93_HUMAN (1852-2283): 1.85e-69: 249: 17.38		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		800447 ZN227_HUMAN (899-1403): 1.19e-59: 224: 9.67		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		1027102 ZN227_HUMAN (899-1403): 1.19e-59: 224: 9.67		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		1027143 ZN420_HUMAN (993-1416): 1.34e-57: 216: 10.80		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		563302 ZNF16_HUMAN (1858-2199): 9.3e-53: 201: 15.95		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		316196 ZN107_HUMAN (300-652): 7.11e-70: 254: 10.93		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18