Protein: HDA11
Histone deacetylase 11 (HD11) (EC 3.5.1.98)

Gene: HDA11, HDAC11
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q96DB2

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594854

GCFC2
Intron Large complex component GCFC2

4

1

High-throughput

0.697

High

1387303

PAXB1
PAX3- and PAX7-binding protein 1

4

1

High-throughput

0.697

High

998660

H31
Histone H3.1

1

20

High-throughput

0.691

High

1315920

RCOR2
REST corepressor 2

1

20

High-throughput

0.691

High

1387291

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

High-throughput

0.691

High

1387284

HDAC6
Protein deacetylase HDAC6

1

20

Small-scale

0.665

High

1387271

OSBL3
Oxysterol-binding protein-related protein 3

3

2

High-throughput

0.662

High

1385158

ATG2B
Autophagy-related protein 2 homolog B

4

2

High-throughput

0.636

High

1387283

TFP11
Tuftelin-interacting protein 11

4

3

High-throughput

0.636

High

1095750

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

20

High-throughput

0.628

High

899520

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.616

High

1387296

DICER
Endoribonuclease Dicer

2

11

High-throughput

0.612

High

273083

CLU
Clustered mitochondria protein homolog

3

5

High-throughput

0.604

High

1112446

MTMR3
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

3

4

High-throughput

0.604

High

1277148

VP35L
VPS35 endosomal protein-sorting factor-like

2

0

High-throughput

0.602

High

1387258

RSRC1
Serine/Arginine-related protein 53

2

0

High-throughput

0.602

High

1387268

CDT1
DNA replication factor Cdt1

2

0

Small-scale

0.598

High

719167

MPIP1
M-phase inducer phosphatase 1

1

3

Small-scale

0.578

High

882081

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.574

High

1007195

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.574

High

1387302

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

2

20

High-throughput

0.574

High

1160543

SMN
Survival motor neuron protein

1

2

High-throughput

0.554

High

1387289

DDX20
Probable ATP-dependent RNA helicase DDX20

1

19

High-throughput

0.554

High

808139

CDN1A
Cyclin-dependent kinase inhibitor 1

1

4

High-throughput

0.541

High

1333942

DHB11
Estradiol 17-beta-dehydrogenase 11

2

1

High-throughput

0.537

High

135309

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

19

High-throughput

0.536

High

167116

GEMI2
Gem-associated protein 2

1

1

High-throughput

0.536

High

229061

AKAP8
A-kinase anchor protein 8

1

6

High-throughput

0.536

High

246850

KDM1A
Lysine-specific histone demethylase 1A

1

14

High-throughput

0.536

High

257925

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.536

High

274699

DNJB6
DnaJ homolog subfamily B member 6

1

16

High-throughput

0.536

High

287992

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

8

High-throughput

0.536

High

321330

ERLN2
Erlin-2

1

8

High-throughput

0.536

High

321625

PRP6
Pre-mRNA-processing factor 6

1

8

High-throughput

0.536

High

325976

UBR5
E3 ubiquitin-protein ligase UBR5

1

7

High-throughput

0.536

High

348650

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.536

High

442787

RB
Retinoblastoma-associated protein

1

13

High-throughput

0.536

High

599855

YBOX3
Y-box-binding protein 3

1

2

High-throughput

0.536

High

667400

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.536

High

679381

DNJB2
DnaJ homolog subfamily B member 2

1

12

High-throughput

0.536

High

697616

PYR1
Multifunctional protein CAD

1

8

High-throughput

0.536

High

714340

PML
Protein PML

1

20

High-throughput

0.536

High

723043

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.536

High

727922

DNJA1
DnaJ homolog subfamily A member 1

1

13

High-throughput

0.536

High

832495

ETV5
ETS translocation variant 5

1

11

High-throughput

0.536

High

855166

NOP2
28S rRNA

1

7

High-throughput

0.536

High

888654

YLPM1
YLP motif-containing protein 1

1

8

High-throughput

0.536

High

913375

MSH6
DNA mismatch repair protein Msh6

1

7

High-throughput

0.536

High

1008281

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

High-throughput

0.536

High

1029903

RUNX1
Runt-related transcription factor 1

1

15

High-throughput

0.536

High

1104643

IKZF1
DNA-binding protein Ikaros

1

18

High-throughput

0.536

High

1111181

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.536

High

1130146

SMC1A
Structural maintenance of chromosomes protein 1A

1

14

High-throughput

0.536

High

1130810

RRP5
Protein RRP5 homolog

1

3

High-throughput

0.536

High

1149155

SF3A1
Splicing factor 3A subunit 1

1

8

High-throughput

0.536

High

1153575

MLF2
Myeloid leukemia factor 2

1

2

High-throughput

0.536

High

1203587

ZN326
DBIRD complex subunit ZNF326

1

6

High-throughput

0.536

High

1204779

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

12

High-throughput

0.536

High

1206747

RRP12
RRP12-like protein

1

1

High-throughput

0.536

High

1217174

RIF1
Telomere-associated protein RIF1

1

4

High-throughput

0.536

High

1245810

ATAD2
ATPase family AAA domain-containing protein 2

1

8

High-throughput

0.536

High

1247277

WDR74
WD repeat-containing protein 74

1

20

High-throughput

0.536

High

1280405

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.536

High

1290323

S2542
Mitochondrial coenzyme A transporter SLC25A42

1

5

High-throughput

0.536

High

1358294

STAG1
Cohesin subunit SA-1

1

3

High-throughput

0.536

High

1359684

PHIP
PH-interacting protein

1

20

High-throughput

0.536

High

1360657

SYNE2
Nesprin-2

1

11

High-throughput

0.536

High

1363596

H1X
Histone H1.10

1

2

High-throughput

0.536

High

1387256

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

10

High-throughput

0.536

High

1387259

ZFR
Zinc finger RNA-binding protein

1

7

High-throughput

0.536

High

1387260

RBM14
RNA-binding protein 14

1

11

High-throughput

0.536

High

1387261

HHIP
Hedgehog-interacting protein

1

4

High-throughput

0.536

High

1387262

WRIP1
ATPase WRNIP1

1

3

High-throughput

0.536

High

1387266

WDR33
pre-mRNA 3' end processing protein WDR33

1

18

High-throughput

0.536

High

1387269

ADNP
Activity-dependent neuroprotector homeobox protein

1

2

High-throughput

0.536

High

1387270

PININ
Pinin

1

1

High-throughput

0.536

High

1387274

SYF1
Pre-mRNA-splicing factor SYF1

1

6

High-throughput

0.536

High

1387276

SMC4
Structural maintenance of chromosomes protein 4

1

12

High-throughput

0.536

High

1387277

MDN1
Midasin

1

11

High-throughput

0.536

High

1387279

RBM22
Pre-mRNA-splicing factor RBM22

1

6

High-throughput

0.536

High

1387280

BCLF1
Bcl-2-associated transcription factor 1

1

2

High-throughput

0.536

High

1387285

DJB11
DnaJ homolog subfamily B member 11

1

11

High-throughput

0.536

High

1387286

ZMYM2
Zinc finger MYM-type protein 2

1

9

High-throughput

0.536

High

1387288

ADDG
Gamma-adducin

1

2

High-throughput

0.536

High

1387292

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

13

High-throughput

0.536

High

1387293

AKP8L
A-kinase anchor protein 8-like

1

6

High-throughput

0.536

High

1387294

TTF2
Transcription termination factor 2

1

20

High-throughput

0.536

High

1387295

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

10

High-throughput

0.536

High

1387297

SRRM2
Serine/arginine repetitive matrix protein 2

1

18

High-throughput

0.536

High

1387298

SMC3
Structural maintenance of chromosomes protein 3

1

14

High-throughput

0.536

High

1387299

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.536

High

1387300

TR150
Thyroid hormone receptor-associated protein 3

1

8

High-throughput

0.536

High

1387304

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

10

High-throughput

0.536

High

1312164

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.518

High

1043724

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1095162

RED
Protein Red

1

0

High-throughput

0.513

High

1105366

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.513

High

1387275

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.513

High

1161178

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.508

High

944540

GEMI4
Gem-associated protein 4

1

1

High-throughput

0.506

High

122539

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

1

High-throughput

0.489

High

175154

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.489

High

229785

CALU
Calumenin

1

3

High-throughput

0.489

High

259034

DNJA2
DnaJ homolog subfamily A member 2

1

13

High-throughput

0.489

High

333699

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

1

High-throughput

0.489

High

347237

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.489

High

615432

SON
Protein SON

1

4

High-throughput

0.489

High

821496

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

841418

RBM34
RNA-binding protein 34

1

10

High-throughput

0.489

High

890384

NU153
Nuclear pore complex protein Nup153

1

17

High-throughput

0.489

High

895279

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

2

High-throughput

0.489

High

916021

NUP98
Nuclear pore complex protein Nup98-Nup96

1

7

High-throughput

0.489

High

1036382

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

3

High-throughput

0.489

High

1125029

RCN2
Reticulocalbin-2

1

3

High-throughput

0.489

High

1145652

RCN1
Reticulocalbin-1

1

3

High-throughput

0.489

High

1199231

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

1

High-throughput

0.489

High

1219870

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.489

High

1242084

TTC27
Tetratricopeptide repeat protein 27

1

9

High-throughput

0.489

High

1316276

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

7

High-throughput

0.489

High

1323432

NUP93
Nuclear pore complex protein Nup93

1

1

High-throughput

0.489

High

1341122

WDR36
WD repeat-containing protein 36

1

8

High-throughput

0.489

High

1365725

GCN1
Stalled ribosome sensor GCN1

1

12

High-throughput

0.489

High

1372361

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.489

High

1381570

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

8

High-throughput

0.489

High

1387257

DDX27
Probable ATP-dependent RNA helicase DDX27

1

13

High-throughput

0.489

High

1387267

CLPB
Mitochondrial disaggregase

1

3

High-throughput

0.489

High

1387272

HEAT1
HEAT repeat-containing protein 1

1

1

High-throughput

0.489

High

1387273

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

7

High-throughput

0.489

High

1387278

RBM28
RNA-binding protein 28

1

6

High-throughput

0.489

High

1387281

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

4

High-throughput

0.489

High

1387301

SGT1
Protein SGT1 homolog

1

4

High-throughput

0.489

High

284342

GEMI
Geminin

1

1

Small-scale

0.479

High

837783

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

5

High-throughput

0.479

High

1387290

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

13

Small-scale

0.479

High

1349894

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

0

Small-scale

0.458

High

1150681

TRBP2
RISC-loading complex subunit TARBP2

1

9

High-throughput

0.445

High

1217011

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

2

High-throughput

0.445

High

1312928

RB12B
RNA-binding protein 12B

1

9

High-throughput

0.437

High

351149

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.426

High

1382441

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.426

High

257156

CCD22
Coiled-coil domain-containing protein 22

1

11

High-throughput

0.407

High

299569

TRIO
Triple functional domain protein

1

14

High-throughput

0.407

High

607708

DCAM
S-adenosylmethionine decarboxylase proenzyme

2

0

High-throughput

0.328

High

1312808

NRM
Nurim

2

0

High-throughput

0.316

High

1364760

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.282

High

139580

PESC
Pescadillo homolog

1

0

High-throughput

0.279

Low

141046

NOP56
Nucleolar protein 56

1

0

High-throughput

0.279

Low

1208795

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.279

Low

1335446

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.279

Low

1356920

NU133
Nuclear pore complex protein Nup133

1

0

High-throughput

0.279

Low

1359174

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.279

Low

1387263

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.279

Low

1387264

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.279

Low

1387265

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.279

Low

1387287

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.249

Low

945904

INHBE
Inhibin beta E chain

1

0

High-throughput

0.232

Low

1387282

RBAS1
Putative uncharacterized protein encoded by RBM12B-AS1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025