HitPredict

Interactor 1: NUAK1 (O60285)
NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)
Gene: NUAK1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 661 Hs			1 247
+	Hs
		229938 NUAK1_HUMAN (1-661): 0: 581: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		229942 NUAK1_HUMAN (1-661): 0: 581: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Mm
		910266 NUAK1_MOUSE (1-661): 0: 557: 90.79		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		229927 NUAK1_HUMAN (1-661): 0: 581: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Xl
		223344 Q804T2_XENLA (4-658): 1.2e-161: 483: 25.67		O57468_XENLA (1-244): 4.25e-141: 397: 63.12
+	Hs
		647862 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		910231 MARK3_MOUSE (4-658): 2.75e-156: 470: 27.09		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Mm
		910308 MARK4_MOUSE (4-655): 2.73e-155: 468: 27.01		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		647860 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		905331 MARK3_MOUSE (4-658): 2.75e-156: 470: 27.09		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Hs
		904994 MARK4_HUMAN (4-655): 1.51e-155: 468: 27.16		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		935481 MARK3_MOUSE (4-658): 2.75e-156: 470: 27.09		1433F_MOUSE (1-246): 1.51e-136: 385: 86.99
+	Hs
		647879 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Mm
		935569 MARK4_MOUSE (4-655): 2.73e-155: 468: 27.01		1433F_MOUSE (1-246): 1.51e-136: 385: 86.99
+	Hs
		647835 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		647869 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		926780 MARK3_MOUSE (4-658): 2.75e-156: 470: 27.09		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Mm
		975157 MARK3_MOUSE (4-658): 2.75e-156: 470: 27.09		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Hs
		646650 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		647836 MARK3_HUMAN (4-658): 1.17e-156: 471: 27.09		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16