Interactor 1: MGRN1 (O60291)
E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1)
Gene: MGRN1

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 17229889, 19703557, 25416956, 37219487, 19549727
Identification Methods pull down, enzymatic study, affinity chromatography technology, two hybrid, unspecified method, validated two hybrid, two hybrid prey pooling approach, two hybrid array, phage display
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008333 - endosome to lysosome transport
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 552
Hs

1 390
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024