HitPredict

Interactor 1: ZC3H1 (O60293)
Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2)
Gene: ZFC3H1

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0005634 - nucleus GO:0006396 - RNA processing
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1989 Hs			1 235
+	Hs
		230430 ZC3H1_HUMAN (1-1989): 0: 3886: 100.00		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		230364 ZC3H1_HUMAN (1-1989): 0: 3886: 100.00		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Sp
		194786 RED1_SCHPO (1142-1221): 3.52e-29: 128: 39.51		RRP41_SCHPO (8-235): 3.68e-65: 204: 23.95
+	Sp
		194811 RED1_SCHPO (1142-1221): 3.52e-29: 128: 39.51		RRP46_SCHPO (34-235): 1.7e-49: 163: 29.61
+	Sp
		252323 RED1_SCHPO (1142-1221): 3.52e-29: 128: 39.51		RRP45_SCHPO (6-234): 4.64e-47: 158: 12.96
+	Sp
		1350838 RED1_SCHPO (1142-1221): 3.52e-29: 128: 39.51		MTR3_SCHPO (23-235): 2.47e-42: 145: 18.58