Protein: CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1]

Gene: CR3L1, CREB3L1
Organism: Homo sapiens
Interactions: 211
UniProt ID: Q96BA8

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1258535

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

2

19

High-throughput

0.811

High

1384322

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

15

Small-scale

0.778

High

1236263

MFSD5
Molybdate-anion transporter

4

1

High-throughput

0.700

High

720578

TSPO
Translocator protein

4

1

High-throughput

0.698

High

60593

TM218
Transmembrane protein 218

4

0

High-throughput

0.675

High

1381010

S35B4
Nucleotide sugar transporter SLC35B4

3

4

High-throughput

0.675

High

1384344

TM147
BOS complex subunit TMEM147

4

0

High-throughput

0.668

High

1384377

PGAP2
Acyltransferase PGAP2

3

1

High-throughput

0.667

High

1132571

FXYD3
FXYD domain-containing ion transport regulator 3

3

3

High-throughput

0.661

High

1310912

ZNT8
Proton-coupled zinc antiporter SLC30A8

4

2

High-throughput

0.647

High

230387

CREB3
Cyclic AMP-responsive element-binding protein 3

1

16

High-throughput

0.647

High

1228202

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

18

High-throughput

0.647

High

225659

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.646

High

949272

MYPR
Myelin proteolipid protein

4

1

High-throughput

0.644

High

123486

GPR25
Probable G-protein coupled receptor 25

4

4

High-throughput

0.637

High

126163

AP3B1
AP-3 complex subunit beta-1

2

3

High-throughput

0.628

High

1380069

FBXW7
F-box/WD repeat-containing protein 7

2

12

High-throughput

0.628

High

1384382

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

3

High-throughput

0.628

High

1384385

TRRAP
Transformation/transcription domain-associated protein

2

6

High-throughput

0.628

High

1384345

FHR5
Complement factor H-related protein 5

3

6

High-throughput

0.616

High

1384347

FXYD6
FXYD domain-containing ion transport regulator 6

3

3

High-throughput

0.616

High

125043

KCNK1
Potassium channel subfamily K member 1

2

1

High-throughput

0.606

High

160320

GOSR2
Golgi SNAP receptor complex member 2

2

1

High-throughput

0.606

High

166977

MGST3
Glutathione S-transferase 3, mitochondrial

2

3

High-throughput

0.606

High

180010

BET1
BET1 homolog

2

3

High-throughput

0.606

High

226350

SNG1
Synaptogyrin-1

2

1

High-throughput

0.606

High

252620

TSN2
Tetraspanin-2

2

6

High-throughput

0.606

High

280298

SC22B
Vesicle-trafficking protein SEC22b

2

3

High-throughput

0.606

High

378159

TNFA
Tumor necrosis factor

2

4

High-throughput

0.606

High

390718

TFR1
Transferrin receptor protein 1

2

2

High-throughput

0.606

High

423822

APOD
Apolipoprotein D

2

4

High-throughput

0.606

High

538850

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

2

5

High-throughput

0.606

High

549458

CD20
B-lymphocyte antigen CD20

2

1

High-throughput

0.606

High

636247

MAL
Myelin and lymphocyte protein

2

5

High-throughput

0.606

High

642270

COMT
Catechol O-methyltransferase

2

1

High-throughput

0.606

High

662356

VAMP1
Vesicle-associated membrane protein 1

2

4

High-throughput

0.606

High

722568

CTR1
High affinity cationic amino acid transporter 1

2

4

High-throughput

0.606

High

832645

AQP2
Aquaporin-2

2

4

High-throughput

0.606

High

849028

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

3

High-throughput

0.606

High

934260

BI1
Bax inhibitor 1

2

3

High-throughput

0.606

High

949016

SC61G
Protein transport protein Sec61 subunit gamma

2

1

High-throughput

0.606

High

989370

VAMP2
Vesicle-associated membrane protein 2

2

1

High-throughput

0.606

High

1005403

CP4F2
Cytochrome P450 4F2

2

2

High-throughput

0.606

High

1007450

S35B1
Solute carrier family 35 member B1

2

2

High-throughput

0.606

High

1031674

ILRL1
Interleukin-1 receptor-like 1

2

4

High-throughput

0.606

High

1050048

PLP2
Proteolipid protein 2

2

3

High-throughput

0.606

High

1092073

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

1

High-throughput

0.606

High

1092799

MALL
MAL-like protein

2

5

High-throughput

0.606

High

1097255

S13A2
Solute carrier family 13 member 2

2

1

High-throughput

0.606

High

1100704

STX3
Syntaxin-3

2

3

High-throughput

0.606

High

1127849

ERG1
Squalene monooxygenase

2

1

High-throughput

0.606

High

1142909

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.606

High

1155023

ADIPO
Adiponectin

2

2

High-throughput

0.606

High

1164291

LTC4S
Leukotriene C4 synthase

2

2

High-throughput

0.606

High

1198937

ORML2
ORM1-like protein 2

2

2

High-throughput

0.606

High

1216446

TSPO2
Translocator protein 2

2

1

High-throughput

0.606

High

1219817

PLPP4
Phospholipid phosphatase 4

2

2

High-throughput

0.606

High

1272372

FA2H
Fatty acid 2-hydroxylase

2

2

High-throughput

0.606

High

1275387

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

2

High-throughput

0.606

High

1292123

ANR46
Ankyrin repeat domain-containing protein 46

2

10

High-throughput

0.606

High

1328714

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

4

High-throughput

0.606

High

1329295

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

5

High-throughput

0.606

High

1331628

ZDH22
Palmitoyltransferase ZDHHC22

2

6

High-throughput

0.606

High

1348034

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

4

High-throughput

0.606

High

1352332

RHBL4
Rhomboid-related protein 4

2

2

High-throughput

0.606

High

1359023

TM239
Transmembrane protein 239

2

2

High-throughput

0.606

High

1359659

GIMA1
GTPase IMAP family member 1

2

1

High-throughput

0.606

High

1380437

MAL2
Protein MAL2

2

5

High-throughput

0.606

High

1381082

TM203
Transmembrane protein 203

2

1

High-throughput

0.606

High

1384324

YIPF6
Protein YIPF6

2

1

High-throughput

0.606

High

1384325

CK024
Uncharacterized protein C11orf24

2

1

High-throughput

0.606

High

1384327

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

3

High-throughput

0.606

High

1384330

RUSF1
RUS family member 1

2

2

High-throughput

0.606

High

1384331

TMM19
Transmembrane protein 19

2

1

High-throughput

0.606

High

1384333

SC22A
Vesicle-trafficking protein SEC22a

2

3

High-throughput

0.606

High

1384334

ZDH15
Palmitoyltransferase ZDHHC15

2

1

High-throughput

0.606

High

1384335

CKLF3
CKLF-like MARVEL transmembrane domain-containing protein 3

2

4

High-throughput

0.606

High

1384337

NEUR1
Sialidase-1

2

2

High-throughput

0.606

High

1384338

MGST2
Microsomal glutathione S-transferase 2

2

3

High-throughput

0.606

High

1384341

VKOR1
Vitamin K epoxide reductase complex subunit 1

2

1

High-throughput

0.606

High

1384342

TM208
Transmembrane protein 208

2

2

High-throughput

0.606

High

1384343

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

2

1

High-throughput

0.606

High

1384348

TM222
Transmembrane protein 222

2

1

High-throughput

0.606

High

1384350

UN93B
Protein unc-93 homolog B1

2

1

High-throughput

0.606

High

1384352

ARV1
Protein ARV1

2

1

High-throughput

0.606

High

1384358

S35C2
Solute carrier family 35 member C2

2

1

High-throughput

0.606

High

1384360

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

3

High-throughput

0.606

High

1384361

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

3

High-throughput

0.606

High

1384362

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

2

High-throughput

0.606

High

1384365

S39A9
Zinc transporter ZIP9

2

4

High-throughput

0.606

High

1384366

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

2

3

High-throughput

0.606

High

1384369

TECR
Very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.606

High

1384371

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

2

High-throughput

0.606

High

1384372

ORML1
ORM1-like protein 1

2

2

High-throughput

0.606

High

1384376

NAT8
N-acetyltransferase 8

2

1

High-throughput

0.606

High

1384378

AGRE2
Adhesion G protein-coupled receptor E2

2

1

High-throughput

0.606

High

1384379

ERG28
Ergosterol biosynthetic protein 28 homolog

2

2

High-throughput

0.606

High

1384380

STX8
Syntaxin-8

2

3

High-throughput

0.606

High

1384381

DOLK
Dolichol kinase

2

1

High-throughput

0.606

High

1384389

TM14A
Transmembrane protein 14A

2

5

High-throughput

0.606

High

144468

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.580

High

156564

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.580

High

258660

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

327404

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.580

High

329651

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.580

High

843344

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.580

High

941758

TM50B
Transmembrane protein 50B

2

0

High-throughput

0.580

High

944409

SYJ2B
Synaptojanin-2-binding protein

2

0

High-throughput

0.580

High

1122476

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.580

High

1164221

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.580

High

1195541

CTXN3
Cortexin-3

2

0

High-throughput

0.580

High

1244520

CNIH2
Protein cornichon homolog 2

2

0

High-throughput

0.580

High

1245904

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.580

High

1249428

OLFM4
Olfactomedin-4

2

0

High-throughput

0.580

High

1251302

HACD2
Very-long-chain

2

0

High-throughput

0.580

High

1274085

MOT13
Monocarboxylate transporter 13

2

0

High-throughput

0.580

High

1313632

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

1324426

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.580

High

1333264

T229B
Transmembrane protein 229B

2

0

High-throughput

0.580

High

1358697

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

2

0

High-throughput

0.580

High

1382712

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

2

0

High-throughput

0.580

High

1384332

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

0

High-throughput

0.580

High

1384353

TNMD
Tenomodulin

2

0

High-throughput

0.580

High

1384354

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.580

High

1384357

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.580

High

1384359

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.580

High

1384368

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.580

High

1384384

GOT1B
Vesicle transport protein GOT1B

2

0

High-throughput

0.580

High

1384386

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.580

High

1384387

PEX16
Peroxisomal membrane protein PEX16

2

0

High-throughput

0.580

High

1384388

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

1384390

TX264
Testis-expressed protein 264

2

0

High-throughput

0.580

High

1231276

BLT3A
Bridge-like lipid transfer protein family member 3A

2

3

High-throughput

0.574

High

1363551

FAM3C
Protein FAM3C

2

2

High-throughput

0.573

High

688408

PPLA
Phospholamban

1

1

High-throughput

0.573

High

1055256

MTG8
Protein CBFA2T1

1

1

High-throughput

0.573

High

1361463

TM234
Transmembrane protein 234

1

1

High-throughput

0.573

High

1161353

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.561

High

164952

TR10C
Tumor necrosis factor receptor superfamily member 10C

2

2

High-throughput

0.553

High

189767

STX7
Syntaxin-7

2

3

High-throughput

0.553

High

216325

MGA
Maltase-glucoamylase

2

2

High-throughput

0.553

High

277059

ENTP3
Ectonucleoside triphosphate diphosphohydrolase 3

2

1

High-throughput

0.553

High

455929

ASGR1
Asialoglycoprotein receptor 1

2

5

High-throughput

0.553

High

539487

ITAM
Integrin alpha-M

2

3

High-throughput

0.553

High

622089

CD53
Leukocyte surface antigen CD53

2

6

High-throughput

0.553

High

641471

CD72
B-cell differentiation antigen CD72

2

7

High-throughput

0.553

High

932749

EMP3
Epithelial membrane protein 3

2

3

High-throughput

0.553

High

1030375

PMP22
Peripheral myelin protein 22

2

3

High-throughput

0.553

High

1035243

RHD
Blood group Rh(D) polypeptide

2

1

High-throughput

0.553

High

1064609

TICN1
Testican-1

2

2

High-throughput

0.553

High

1205526

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

1

High-throughput

0.553

High

1247768

PAQR6
Membrane progestin receptor delta

2

2

High-throughput

0.553

High

1340045

O10AG
Olfactory receptor 10AG1

2

1

High-throughput

0.553

High

1340708

CC4L
C-C motif chemokine 4-like

2

5

High-throughput

0.553

High

1347187

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

1

High-throughput

0.553

High

1350628

SFXN5
Sideroflexin-5

2

2

High-throughput

0.553

High

1351758

GP151
G-protein coupled receptor 151

2

1

High-throughput

0.553

High

1359757

S13A3
Na(+)/dicarboxylate cotransporter 3

2

1

High-throughput

0.553

High

1371125

NINJ1
Ninjurin-1

2

1

High-throughput

0.553

High

1384326

GIMA5
GTPase IMAP family member 5

2

1

High-throughput

0.553

High

1384329

PLPR2
Phospholipid phosphatase-related protein type 2

2

2

High-throughput

0.553

High

1384336

AQP10
Aquaporin-10

2

5

High-throughput

0.553

High

1384356

S39A2
Zinc transporter ZIP2

2

4

High-throughput

0.553

High

1384363

SEM4G
Semaphorin-4G

2

1

High-throughput

0.553

High

1384364

TM14B
Transmembrane protein 14B

2

5

High-throughput

0.553

High

1384370

NINJ2
Ninjurin-2

2

1

High-throughput

0.553

High

1384373

TM14C
Transmembrane protein 14C

2

5

High-throughput

0.553

High

1384374

LPAR3
Lysophosphatidic acid receptor 3

2

1

High-throughput

0.553

High

1384375

FETUB
Fetuin-B

2

1

High-throughput

0.553

High

1312806

NRM
Nurim

1

0

High-throughput

0.549

High

1328176

JAGN1
Protein jagunal homolog 1

1

0

High-throughput

0.549

High

564177

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.541

High

116736

I3L0A0
HCG2044781

1

9

High-throughput

0.515

High

1065909

Q08AM2
ADAM33 protein

1

2

High-throughput

0.515

High

1233688

Q6IB11
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.515

High

775458

DDIT3
DNA damage-inducible transcript 3 protein

1

7

High-throughput

0.501

High

63834

PEDS1
Plasmanylethanolamine desaturase 1

1

1

High-throughput

0.481

High

130201

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.481

High

528705

PPGB
Lysosomal protective protein

1

1

High-throughput

0.481

High

1384340

CYBC1
Cytochrome b-245 chaperone 1

1

1

High-throughput

0.481

High

1384346

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

2

High-throughput

0.481

High

1384339

EPAS1
Endothelial PAS domain-containing protein 1

1

3

Small-scale

0.479

High

1196850

Q4VAQ0
COL8A2 protein

1

2

High-throughput

0.470

High

1202529

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

1203331

TM128
Transmembrane protein 128

1

0

High-throughput

0.460

High

1338034

TMIE
Transmembrane inner ear expressed protein

1

0

High-throughput

0.460

High

1384351

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

1384355

VEZA
Vezatin

1

0

High-throughput

0.460

High

668792

CO8A2
Collagen alpha-2(VIII) chain

1

2

High-throughput

0.439

High

1350290

C99L2
CD99 antigen-like protein 2

1

1

High-throughput

0.439

High

3500

A0A0S2Z5R8
CD99 antigen-like protein 2

1

1

High-throughput

0.417

High

97204

E9PRZ2
Post-GPI attachment to proteins 2

1

1

High-throughput

0.417

High

602255

TMM11
Transmembrane protein 11, mitochondrial

3

0

High-throughput

0.345

High

49681

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

74187

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

168111

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

2

0

High-throughput

0.316

High

335572

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

351719

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.316

High

377870

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.316

High

1127333

WFDC2
WAP four-disulfide core domain protein 2

2

0

High-throughput

0.316

High

1204490

RNS10
Inactive ribonuclease-like protein 10

2

0

High-throughput

0.316

High

1209038

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

2

0

High-throughput

0.316

High

1313961

PAQRA
Monocyte to macrophage differentiation factor 2

2

0

High-throughput

0.316

High

1384323

TLCD1
TLC domain-containing protein 1

2

0

High-throughput

0.316

High

1384328

S35A4
Probable UDP-sugar transporter protein SLC35A4

2

0

High-throughput

0.316

High

1384349

SNAB
Beta-soluble NSF attachment protein

2

0

High-throughput

0.316

High

1384367

S52A1
Solute carrier family 52, riboflavin transporter, member 1

2

0

High-throughput

0.316

High

1384383

MA2B2
Epididymis-specific alpha-mannosidase

2

0

High-throughput

0.316

High

369981

CO5
Complement C5

1

0

High-throughput

0.299

High

914697

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025