HitPredict

Interactor 1: TRAK2 (O60296)
Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein)
Gene: TRAK2

Interactor 2: KIF5A (Q12840)
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032839 - dendrite cytoplasm GO:1904115 - axon cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 1032
+	Rn
		1163333 TRAK2_RAT (1-914): 2.58e-159: 492: 86.56		KIF5A_RAT (1-1032): 8.04e-149: 471: 96.42
+	Hs
		230481 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Mm
		193275 HAP1_MOUSE (95-387): 1.41e-62: 225: 27.86		KIF5A_MOUSE (1-1032): 6.83e-152: 479: 97.29
+	Hs
		229823 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20
+	Hs
		230487 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Rn
		1102446 TRAK2_RAT (1-914): 2.58e-159: 492: 86.56		KINH_RAT (623-1016): 2.52e-14: 79.9: 10.25
+	Hs
		1017532 ITSN1_HUMAN (259-658): 1.38e-14: 80.7: 9.22		KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00
+	Hs
		855644 DCTN1_HUMAN (101-551): 8.67e-12: 71.5: 14.47		KIF11_HUMAN (2-876): 1.97e-155: 489: 27.47
+	Hs
		231757 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		216984 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Hs
		231597 HOOK3_HUMAN (62-402): 2.97e-17: 88.9: 16.25		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		231518 DCTN1_HUMAN (101-551): 8.67e-12: 71.5: 14.47		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		216943 HOOK3_HUMAN (62-402): 2.97e-17: 88.9: 16.25		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Rn
		869341 HAP1_RAT (95-387): 1.58e-64: 231: 29.10		KIF5C_RAT (477-1017): 4.16e-16: 85.6: 8.63
+	Rn
		869352 HAP1_RAT (95-387): 1.58e-64: 231: 29.10		KINH_RAT (623-1016): 2.52e-14: 79.9: 10.25
+	Hs
		229894 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20
+	Hs
		702992 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Dm
		566098 MILT_DROME (86-360): 2.25e-28: 125: 30.18		KINH_DROME (551-1029): 8.98e-11: 68.3: 9.43
+	Hs
		702938 HOOK3_HUMAN (62-402): 2.97e-17: 88.9: 16.25		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Hs
		229863 ITSN1_HUMAN (259-658): 1.38e-14: 80.7: 9.22		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20