Protein: KIF3A
Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)

Gene: KIF3A
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q9Y496

Gene Ontology (top 5):
GO:0003777 - microtubule motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005814 - centriole

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

176625

KIF3B
Kinesin-like protein KIF3B

6

19

Small-scale

0.953

High

164168

KIF3C
Kinesin-like protein KIF3C

4

16

High-throughput

0.909

High

1389127

KBP
KIF-binding protein

3

11

High-throughput

0.770

High

1369549

KIFA3
Kinesin-associated protein 3

7

15

Small-scale

0.749

High

857603

NOTC1
Neurogenic locus notch homolog protein 1

1

3

High-throughput

0.691

High

712905

CASP1
Caspase-1

3

1

High-throughput

0.667

High

1389822

DTBP1
Dysbindin

3

2

High-throughput

0.667

High

186172

LX15B
Polyunsaturated fatty acid lipoxygenase ALOX15B

2

1

High-throughput

0.628

High

705927

TNR8
Tumor necrosis factor receptor superfamily member 8

2

2

High-throughput

0.628

High

1017327

H33
Histone H3.3

2

10

High-throughput

0.628

High

1118011

PKP1
Plakophilin-1

2

6

High-throughput

0.628

High

1491320

PKP3
Plakophilin-3

2

9

High-throughput

0.628

High

1491349

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

2

4

High-throughput

0.628

High

1211047

CE170
Centrosomal protein of 170 kDa

1

2

High-throughput

0.618

High

303206

RGS20
Regulator of G-protein signaling 20

2

5

High-throughput

0.611

High

881344

FAS
Fatty acid synthase

2

1

High-throughput

0.611

High

423523

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.602

High

252931

EXOC3
Exocyst complex component 3

2

0

High-throughput

0.602

High

334644

LYPA2
Acyl-protein thioesterase 2

2

0

High-throughput

0.602

High

582646

PPAP
Prostatic acid phosphatase

2

0

High-throughput

0.602

High

787727

SPB5
Serpin B5

2

0

High-throughput

0.602

High

870501

PPCE
Prolyl endopeptidase

2

0

High-throughput

0.602

High

1098696

SBP1
Methanethiol oxidase

2

0

High-throughput

0.602

High

1214628

HENMT
Small RNA 2'-O-methyltransferase

2

0

High-throughput

0.602

High

1234717

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

0

High-throughput

0.602

High

1275350

APTX
Aprataxin

2

0

High-throughput

0.602

High

1353685

LRC15
Leucine-rich repeat-containing protein 15

2

0

High-throughput

0.602

High

1461824

PADI3
Protein-arginine deiminase type-3

2

0

High-throughput

0.602

High

1448591

DISC1
Disrupted in schizophrenia 1 protein

2

4

High-throughput

0.590

High

243384

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

69848

ZN785
Zinc finger protein 785

2

5

High-throughput

0.574

High

326804

DUS14
Dual specificity protein phosphatase 14

2

4

High-throughput

0.574

High

1120998

TRI29
Tripartite motif-containing protein 29

2

12

High-throughput

0.574

High

1226841

ATG9B
Autophagy-related protein 9B

2

1

High-throughput

0.574

High

1286489

DSG4
Desmoglein-4

2

3

High-throughput

0.574

High

1366148

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

8

High-throughput

0.554

High

126204

AP3B1
AP-3 complex subunit beta-1

1

5

Small-scale

0.552

High

822924

VHL
von Hippel-Lindau disease tumor suppressor

1

5

Small-scale

0.552

High

1038584

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

7

Small-scale

0.552

High

279549

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

874020

NRIP1
Nuclear receptor-interacting protein 1

1

1

High-throughput

0.541

High

943632

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

4

High-throughput

0.541

High

988062

GRB2
Growth factor receptor-bound protein 2

1

7

High-throughput

0.541

High

1437692

PKHA5
Pleckstrin homology domain-containing family A member 5

1

19

High-throughput

0.541

High

64585

MP3B2
Microtubule-associated protein 1 light chain 3 beta 2

1

3

High-throughput

0.536

High

124983

GTPB1
GTP-binding protein 1

1

3

High-throughput

0.536

High

171792

GAK
Cyclin-G-associated kinase

1

5

High-throughput

0.536

High

568992

ANXA8
Annexin A8

1

6

High-throughput

0.536

High

877407

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.536

High

882585

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.536

High

981751

RAN
GTP-binding nuclear protein Ran

1

12

High-throughput

0.536

High

1213204

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

2

High-throughput

0.536

High

1260575

SSH2
Protein phosphatase Slingshot homolog 2

1

4

High-throughput

0.536

High

1371798

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

0.536

High

1384779

ARL8A
ADP-ribosylation factor-like protein 8A

1

3

High-throughput

0.536

High

1419611

NUF2
Kinetochore protein Nuf2

1

9

High-throughput

0.536

High

1451068

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

15

High-throughput

0.536

High

1453964

RN181
E3 ubiquitin-protein ligase RNF181

1

1

High-throughput

0.536

High

1460061

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

6

High-throughput

0.536

High

1121660

MORC3
MORC family CW-type zinc finger protein 3

1

0

High-throughput

0.518

High

1123557

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

48399

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

0

High-throughput

0.513

High

902408

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

0

High-throughput

0.513

High

1121630

DHX34
Probable ATP-dependent RNA helicase DHX34

1

0

High-throughput

0.513

High

1226612

MAP1S
Microtubule-associated protein 1S

1

0

High-throughput

0.513

High

1254142

CAN12
Calpain-12

1

0

High-throughput

0.513

High

1358941

SMIP5
Sperm-associated microtubule inner protein 5

1

0

High-throughput

0.513

High

1361549

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.513

High

1397266

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1404713

PAFA2
Platelet-activating factor acetylhydrolase 2, cytoplasmic

1

0

High-throughput

0.513

High

1413686

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.513

High

1446146

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

1451194

BEX4
Protein BEX4

1

0

High-throughput

0.513

High

1461531

INTU
Protein inturned

1

0

High-throughput

0.513

High

1491350

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

1400380

NEK1
Serine/threonine-protein kinase Nek1

1

7

Small-scale

0.508

High

1414921

DUS26
Dual specificity protein phosphatase 26

1

4

Small-scale

0.506

High

516736

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

2

High-throughput

0.504

High

249219

DSCAM
Cell adhesion molecule DSCAM

1

3

High-throughput

0.494

High

696956

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.489

High

848754

MAGA9
Melanoma-associated antigen 9

1

5

High-throughput

0.489

High

1179886

INSY1
Inhibitory synaptic factor 1

1

4

High-throughput

0.489

High

1338719

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

4

High-throughput

0.489

High

1461608

AT7L1
Ataxin-7-like protein 1

1

1

High-throughput

0.489

High

1121387

TRI14
Tripartite motif-containing protein 14

1

7

High-throughput

0.481

High

1159146

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

7

Small-scale

0.481

High

228053

SSNA1
Microtubule nucleation factor SSNA1

1

1

High-throughput

0.479

High

412866

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.479

High

564606

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.479

High

732744

ARRB2
Beta-arrestin-2

1

1

Small-scale

0.479

High

765151

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

791869

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

890620

RBP2
E3 SUMO-protein ligase RanBP2

1

5

Small-scale

0.479

High

980596

H4
Histone H4

1

2

High-throughput

0.479

High

1104944

XRCC4
DNA repair protein XRCC4

1

1

High-throughput

0.479

High

1110772

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

1150508

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.479

High

1214611

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.479

High

1227768

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.479

High

1256236

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1258991

H32
Histone H3.2

1

10

High-throughput

0.479

High

1361268

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

1391882

AURKB
Aurora kinase B

1

2

High-throughput

0.479

High

1399132

SCLT1
Sodium channel and clathrin linker 1

1

4

High-throughput

0.479

High

1416784

RFIP5
Rab11 family-interacting protein 5

1

2

Small-scale

0.479

High

1434318

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.479

High

1461479

DNPEP
Aspartyl aminopeptidase

1

1

High-throughput

0.479

High

892741

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

1460327

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1057066

FMR1
Fragile X messenger ribonucleoprotein 1

1

17

High-throughput

0.457

High

530651

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

1145451

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.445

High

1251623

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

1

3

High-throughput

0.437

High

1383722

VP33A
Vacuolar protein sorting-associated protein 33A

1

3

High-throughput

0.437

High

1392373

BORC6
BLOC-1-related complex subunit 6

1

1

High-throughput

0.437

High

1446566

MED4
Mediator of RNA polymerase II transcription subunit 4

1

4

High-throughput

0.437

High

947084

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

75591

B3KSW4
Regulator of G protein signaling 20

1

4

High-throughput

0.407

High

1167136

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

1434850

STN1
CST complex subunit STN1

3

0

High-throughput

0.347

High

1207495

CAHM4
Calcium homeostasis modulator protein 4

2

0

High-throughput

0.328

High

1236055

HPHL1
Ferroxidase HEPHL1

2

0

High-throughput

0.328

High

1286418

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

181468

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.279

Low

967285

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

1119620

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.279

Low

1157354

SSX2
Protein SSX2

1

0

High-throughput

0.279

Low

1158834

CART

1

0

High-throughput

0.279

Low

1258716

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low

1350827

PKHO2
Pleckstrin homology domain-containing family O member 2

1

0

High-throughput

0.279

Low

1428941

PIP30
PSME3-interacting protein

1

0

High-throughput

0.279

Low

1459999

F153A
Protein FAM153A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025