HitPredict

Interactor 1: AQR (O60306)
RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160)
Gene: AQR

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1485 Hs			1 344
+	Hs
		230797 AQR_HUMAN (1-1485): 0: 1837: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		230738 AQR_HUMAN (1-1485): 0: 1837: 100.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Sc
		633921 RENT1_YEAST (575-1422): 5.78e-152: 489: 15.15		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Sc
		376676 RENT1_YEAST (575-1422): 5.78e-152: 489: 15.15		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80
+	Sc
		633979 SEN1_YEAST (565-1395): 1.99e-130: 450: 17.54		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Sc
		959989 SEN1_YEAST (565-1395): 1.99e-130: 450: 17.54		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Sc
		376894 SEN1_YEAST (565-1395): 1.99e-130: 450: 17.54		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80
+	Hs
		992866 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		1272321 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		1029025 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		1308759 HELZ2_HUMAN (967-1477): 8.29e-56: 217: 13.25		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		516622 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		680472 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		TIA1_HUMAN (2-116): 2.8e-11: 66.1: 17.50
+	Hs
		952063 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		1028831 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		1029107 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		1031468 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		516699 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		963574 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		TIAR_HUMAN (102-272): 2.65e-09: 59.9: 13.19
+	Hs
		952134 MOV10_HUMAN (604-891): 3.01e-14: 80.3: 13.04		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84