Protein: EXT2
Exostosin-2 (EC 2.4.1.224) (Exostosin glycosyltransferase 2) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 2)

Gene: EXT2
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q93063

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000271 - polysaccharide biosynthetic process
GO:0001503 - ossification
GO:0001707 - mesoderm formation
GO:0002062 - chondrocyte differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1157384

EXT1
Exostosin-1

4

12

Small-scale

0.892

High

230832

EXTL3
Exostosin-like 3

1

12

High-throughput

0.691

High

1372140

EXT2
Exostosin-2

1

12

Small-scale

0.618

High

814837

CUX1
Homeobox protein cut-like 1

2

2

High-throughput

0.611

High

183955

S22A2
Solute carrier family 22 member 2

2

3

High-throughput

0.608

High

1372156

INVS
Inversin

2

0

High-throughput

0.602

High

1287765

NOP9
Nucleolar protein 9

2

1

High-throughput

0.574

High

409598

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

6

High-throughput

0.536

High

437756

HEPS
Serine protease hepsin

1

4

High-throughput

0.536

High

519649

LYAG
Lysosomal alpha-glucosidase

1

1

High-throughput

0.536

High

567942

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.536

High

628437

KLK2
Kallikrein-2

1

8

High-throughput

0.536

High

698978

CALX
Calnexin

1

3

High-throughput

0.536

High

1198735

MPPE1
Metallophosphoesterase 1

1

2

High-throughput

0.536

High

1363118

CLC2B
C-type lectin domain family 2 member B

1

5

High-throughput

0.536

High

1372143

TMPSD
Transmembrane protease serine 13

1

4

High-throughput

0.536

High

1372148

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

1372152

DNJB9
DnaJ homolog subfamily B member 9

1

1

High-throughput

0.536

High

1372155

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

1

High-throughput

0.536

High

1090483

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

Small-scale

0.527

High

1281723

GALT5
Polypeptide N-acetylgalactosaminyltransferase 5

1

2

Small-scale

0.527

High

1010997

CRUM1
Protein crumbs homolog 1

1

1

High-throughput

0.515

High

214137

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

224511

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.513

High

341343

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

520953

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

1194696

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.513

High

1308276

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

1369035

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1372147

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.513

High

508381

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

291849

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.493

High

302709

SYUG
Gamma-synuclein

1

0

High-throughput

0.493

High

578622

FABP4
Fatty acid-binding protein, adipocyte

1

0

High-throughput

0.493

High

973072

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.493

High

1372158

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.493

High

168441

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.489

High

342637

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

438903

CD1A
T-cell surface glycoprotein CD1a

1

2

High-throughput

0.489

High

506888

CFC1
Cryptic protein

1

1

High-throughput

0.489

High

1101397

SG2A2
Mammaglobin-A

1

4

High-throughput

0.489

High

1248780

LYZL1
Lysozyme-like protein 1

1

1

High-throughput

0.489

High

1372141

T106A
Transmembrane protein 106A

1

3

High-throughput

0.489

High

1372146

KLK15
Kallikrein-15

1

4

High-throughput

0.489

High

1372154

BTNL2
Butyrophilin-like protein 2

1

1

High-throughput

0.489

High

1372157

PRG3
Proteoglycan 3

1

2

High-throughput

0.489

High

628004

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

218583

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

242503

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

505404

CLC2L
C-type lectin domain family 2 member L

1

5

High-throughput

0.479

High

1308182

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.479

High

1372150

DJB12
DnaJ homolog subfamily B member 12

1

1

High-throughput

0.479

High

686753

CNTF
Ciliary neurotrophic factor

1

1

High-throughput

0.470

High

363676

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

1163792

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.458

High

1226485

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

170909

CLGN
Calmegin

1

3

High-throughput

0.445

High

722564

CTR1
High affinity cationic amino acid transporter 1

1

3

High-throughput

0.445

High

1119449

CASP
Protein CASP

1

2

High-throughput

0.445

High

1131587

MFS10
Major facilitator superfamily domain-containing protein 10

1

3

High-throughput

0.445

High

1236257

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.445

High

1242189

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

1251166

ZNT10
Calcium/manganese antiporter SLC30A10

1

9

High-throughput

0.445

High

1251782

S39A5
Zinc transporter ZIP5

1

12

High-throughput

0.445

High

1289141

OSTA
Organic solute transporter subunit alpha

1

2

High-throughput

0.445

High

1337894

ZNT7
Zinc transporter 7

1

9

High-throughput

0.445

High

1346749

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

9

High-throughput

0.445

High

1363412

S39A7
Zinc transporter SLC39A7

1

12

High-throughput

0.445

High

1372145

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.437

High

1372149

T106B
Transmembrane protein 106B

1

3

High-throughput

0.437

High

222312

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

1311147

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.407

High

1348614

S7A14
Solute carrier family 7 member 14

1

3

High-throughput

0.407

High

1359220

CA054
Uncharacterized protein C1orf54

1

3

High-throughput

0.407

High

1372142

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.407

High

332327

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.328

High

1231770

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.328

High

1257979

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

2

0

High-throughput

0.328

High

1322231

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.328

High

1327345

AFAP1
Actin filament-associated protein 1

2

0

High-throughput

0.328

High

647391

IDS
Iduronate 2-sulfatase

2

0

High-throughput

0.318

High

1372151

GSKIP
GSK3B-interacting protein

1

0

High-throughput

0.282

High

548084

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

570705

EDN3
Endothelin-3

1

0

High-throughput

0.279

Low

1372144

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.279

Low

834017

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.269

Low

1147088

ELOC
Elongin-C

1

0

High-throughput

0.269

Low

261849

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.265

Low

405523

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

808135

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.265

Low

1160538

SMN
Survival motor neuron protein

1

0

High-throughput

0.265

Low

1004926

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1249081

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1372153

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

640249

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.232

Low

839065

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025