HitPredict

Interactor 1: MAST3 (O60307)
Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1)
Gene: MAST3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1309 Hs			1 246
+	Hs
		230856 MAST3_HUMAN (1-1309): 0: 941: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		230857 MAST3_HUMAN (1-1309): 0: 941: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		230855 MAST3_HUMAN (1-1309): 0: 941: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		230863 MAST3_HUMAN (1-1309): 0: 941: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		910182 MAST1_HUMAN (17-1307): 0: 777: 56.65		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683833 MAST1_HUMAN (17-1307): 0: 777: 56.65		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927679 MAST1_HUMAN (17-1307): 0: 777: 56.65		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909684 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683450 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927172 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		164690 MAST4_HUMAN (11-1295): 0: 712: 58.72		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		164684 MAST4_HUMAN (11-1295): 0: 712: 58.72		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647005 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		982637 MAST1_HUMAN (17-1307): 0: 777: 56.65		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		164682 MAST4_HUMAN (11-1295): 0: 712: 58.72		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904719 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982147 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684124 MAST2_HUMAN (14-1307): 0: 755: 57.62		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		164689 MAST4_HUMAN (11-1295): 0: 712: 58.72		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		164685 MAST4_HUMAN (11-1295): 0: 712: 58.72		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62