HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.579

Property	Details
Experiments	29634390, 30196744
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 607
+	Mm
		1169739 KDM1A_MOUSE (1-852): 0: 922: 97.30		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		1146643 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1146696 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1251599 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48
+	Hs
		1272917 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48
+	Dm
		1279319 Q9VF03_DROME (21-301): 3.49e-54: 206: 15.61		EBI_DROME (163-478): 2.44e-58: 209: 15.93
+	Mm
		956825 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Mm
		1161020 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		903369 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45