HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	27632941, 31130994, 31833203, 32453339
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 1102
+	Mm
		1149450 KDM1A_MOUSE (1-852): 0: 922: 97.30		UBP7_MOUSE (1-1102): 0: 1159: 99.00
+	Hs
		1251594 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1272915 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Mm
		1149448 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		UBP7_MOUSE (1-1102): 0: 1159: 99.00
+	Hs
		232266 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		232595 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		232395 KDM1A_HUMAN (1-852): 0: 936: 100.00		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		232596 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41