Protein: MYH4
Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)

Gene: MYH4
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q9Y623

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0003725 - double-stranded RNA binding
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

535958

MYH3
Myosin-3

1

18

High-throughput

0.691

High

556973

MYH7
Myosin-7

1

17

High-throughput

0.691

High

563081

MYH8
Myosin-8

1

15

High-throughput

0.691

High

1149422

SIX1
Homeobox protein SIX1

3

3

High-throughput

0.667

High

1462713

AURKC
Aurora kinase C

3

14

High-throughput

0.667

High

607321

NEUM
Neuromodulin

1

0

High-throughput

0.656

High

870181

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

2

5

High-throughput

0.628

High

1161458

HIF1A
Hypoxia-inducible factor 1-alpha

2

8

High-throughput

0.628

High

1200164

BOREA
Borealin

3

3

High-throughput

0.609

High

1451913

TM260
Protein O-mannosyl-transferase TMEM260

3

3

High-throughput

0.609

High

1034636

AK17A
A-kinase anchor protein 17A

2

3

High-throughput

0.574

High

1048147

TLE3
Transducin-like enhancer protein 3

2

8

High-throughput

0.574

High

1410804

SYT3
Synaptotagmin-3

2

1

High-throughput

0.574

High

64697

PALM3
Paralemmin-3

1

1

High-throughput

0.536

High

276733

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

3

High-throughput

0.536

High

349307

LATS1
Serine/threonine-protein kinase LATS1

1

16

High-throughput

0.536

High

482652

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

2

High-throughput

0.536

High

557552

SRC
Proto-oncogene tyrosine-protein kinase Src

1

5

High-throughput

0.536

High

564621

CFTR
Cystic fibrosis transmembrane conductance regulator

1

11

High-throughput

0.536

High

651743

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

10

High-throughput

0.536

High

1110225

HDAC1
Histone deacetylase 1

1

11

High-throughput

0.536

High

1311669

KIBRA
Protein KIBRA

1

9

High-throughput

0.536

High

1401852

TGS1
Trimethylguanosine synthase

1

1

High-throughput

0.536

High

1459554

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

7

High-throughput

0.536

High

1460799

HSPB8
Heat shock protein beta-8

1

10

High-throughput

0.536

High

1491401

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

9

High-throughput

0.536

High

1023992

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.489

High

1040960

MECOM
Histone-lysine N-methyltransferase MECOM

1

5

High-throughput

0.489

High

1199904

LACB2
Endoribonuclease LACTB2

1

3

High-throughput

0.489

High

1218135

CP141
Cilia- and flagella-associated protein 141

1

2

High-throughput

0.489

High

1230326

K1C40
Keratin, type I cytoskeletal 40

1

10

High-throughput

0.489

High

1288424

TSN33
Tetraspanin-33

1

6

High-throughput

0.489

High

1328780

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

11

High-throughput

0.489

High

1331624

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

9

High-throughput

0.489

High

1399916

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

2

High-throughput

0.489

High

1412086

S39A3
Zinc transporter ZIP3

1

4

High-throughput

0.489

High

1412249

ATGA1
Autophagy-related protein 101

1

1

High-throughput

0.489

High

1414251

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

3

High-throughput

0.489

High

1430180

RSH6A
Radial spoke head protein 6 homolog A

1

5

High-throughput

0.489

High

1433661

E41L1
Band 4.1-like protein 1

1

4

High-throughput

0.489

High

1448018

ASAH2
Neutral ceramidase

1

3

High-throughput

0.489

High

1491798

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

2

High-throughput

0.489

High

323629

TRI37
E3 ubiquitin-protein ligase TRIM37

1

13

High-throughput

0.479

High

326127

UBR5
E3 ubiquitin-protein ligase UBR5

1

3

Small-scale

0.479

High

414928

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

888422

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

1220915

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

1253256

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

9

High-throughput

0.479

High

1313578

SMC5
Structural maintenance of chromosomes protein 5

1

15

High-throughput

0.479

High

1453198

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

1491122

SBDS
Ribosome maturation protein SBDS

1

5

High-throughput

0.479

High

443109

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

2

High-throughput

0.437

High

904222

BAP31
B-cell receptor-associated protein 31

1

11

High-throughput

0.437

High

1008596

NTH
Endonuclease III-like protein 1

1

1

High-throughput

0.437

High

1250225

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

635922

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

769813

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.426

High

1128168

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.426

High

1179084

RSPO1
R-spondin-1

1

5

High-throughput

0.407

High

1367703

ESR2
Estrogen receptor beta

1

9

High-throughput

0.407

High

1088174

CNTN1
Contactin-1

1

0

High-throughput

0.279

Low

1292779

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1316803

SELH
Selenoprotein H

1

0

High-throughput

0.279

Low

1405970

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.279

Low

1431207

MEGF9
Multiple epidermal growth factor-like domains protein 9

1

0

High-throughput

0.279

Low

1453687

THYN1
Thymocyte nuclear protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025