HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21549307
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 852 Hs			1 1026
+	Hs
		232058 KDM1A_HUMAN (1-852): 0: 936: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		232559 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		232364 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD6_HUMAN (61-1021): 0: 664: 22.13
+	Hs
		232524 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		232129 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		1251627 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SMRCD_HUMAN (1-1026): 0: 903: 100.00
+	Hs
		1272938 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SMRCD_HUMAN (1-1026): 0: 903: 100.00
+	Sp
		194465 LSD2_SCHPO (41-844): 1.62e-124: 407: 17.31		FFT3_SCHPO (142-1015): 0: 588: 32.15
+	Mm
		956808 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Mm
		956819 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		SMCA2_MOUSE (60-1024): 0: 692: 24.98
+	Hs
		847025 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		847045 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		846825 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		846839 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		1251639 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		1272954 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		1251632 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		1272944 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		1018598 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		1018623 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CHD3_HUMAN (338-1022): 0: 621: 27.64