HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006915 - apoptotic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 851
+	Hs
		233012 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		232742 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		ANR17_HUMAN (553-836): 3.23e-37: 154: 20.42
+	Hs
		233001 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		RAI14_HUMAN (710-831): 8.96e-21: 100: 27.05
+	Hs
		276190 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		PSD10_HUMAN (675-851): 2.07e-47: 170: 21.47
+	Hs
		257621 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		ANR17_HUMAN (553-836): 3.23e-37: 154: 20.42
+	Hs
		862054 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DAPK1_HUMAN (658-791): 1.53e-24: 112: 31.34
+	Hs
		1130677 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		RAI14_HUMAN (710-831): 8.96e-21: 100: 27.05
+	Hs
		1301444 ERBIN_HUMAN (637-806): 2.73e-09: 64.3: 26.86		Q9H4D1_HUMAN (286-768): 4.3e-29: 126: 14.13
+	Hs
		883609 ERBIN_HUMAN (637-806): 2.73e-09: 64.3: 26.86		RIPK4_HUMAN (246-768): 2.6e-27: 120: 13.97