HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: ZMYM2 (Q9UBW7)
Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)
Gene: ZMYM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	33961781, 18806873, 32891193, 12493763, 34079125, 34709266, 16140033, 16079794
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 1377
+	Mm
		1169777 KDM1A_MOUSE (1-852): 0: 922: 97.30		ZMYM2_MOUSE (1-1377): 0: 1881: 96.08
+	Hs
		232233 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZMYM4_HUMAN (36-1377): 0: 1550: 33.76
+	Mm
		56875 KDM1A_MOUSE (1-852): 0: 922: 97.30		ZMYM4_MOUSE (1-1377): 0: 1542: 32.85
+	Mm
		1169795 KDM1A_MOUSE (1-852): 0: 922: 97.30		ZMYM3_MOUSE (170-1377): 0: 1401: 40.96
+	Hs
		232162 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Mm
		1169740 KDM1A_MOUSE (1-852): 0: 922: 97.30		K1958_MOUSE (795-1351): 2.57e-154: 485: 15.65
+	Mm
		1112336 KDM1A_MOUSE (1-852): 0: 922: 97.30		ZMYM5_MOUSE (504-714): 1.37e-37: 153: 19.07