HitPredict

Interactor 1: HBP1 (O60381)
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
Gene: HBP1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	21967847
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Hs			1 2442
+	Hs
		233833 HBP1_HUMAN (1-514): 0: 889: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		818828 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		989543 SOX4_HUMAN (386-511): 2.32e-32: 131: 25.58		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Rn
		94293 SOX9_RAT (342-512): 1.05e-32: 132: 19.88		F1M9G7_RAT (1-2442): 0: 1076: 95.46
+	Hs
		233870 HBP1_HUMAN (1-514): 0: 889: 100.00		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Dm
		136280 PANG1_DROME (353-504): 4.55e-32: 132: 24.34		O01368_DROME (480-2357): 0: 893: 35.21
+	Hs
		881798 SOX10_HUMAN (387-512): 9.18e-33: 132: 23.02		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		818793 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		989526 SOX4_HUMAN (386-511): 2.32e-32: 131: 25.58		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Dm
		116021 Q9VUD3_DROME (389-514): 3.8e-33: 134: 28.57		M9PH39_DROME (480-2357): 0: 829: 35.44
+	Hs
		170279 SOX5_HUMAN (404-510): 3.14e-35: 142: 31.78		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		1300971 CIC_HUMAN (407-512): 6.93e-40: 156: 33.62		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		727934 SOX6_HUMAN (385-510): 1.46e-36: 146: 30.60		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		727814 SOX5_HUMAN (404-510): 3.14e-35: 142: 31.78		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		881814 SOX10_HUMAN (387-512): 9.18e-33: 132: 23.02		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		818817 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		989539 SOX4_HUMAN (386-511): 2.32e-32: 131: 25.58		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		881831 SOX10_HUMAN (387-512): 9.18e-33: 132: 23.02		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		818841 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		818819 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89