HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: TB22B (Q9NU19)
TBC1 domain family member 22B
Gene: TBC1D22B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1756 Hs			1 505
+	Hs
		551852 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		TB22B_HUMAN (1-505): 9.73e-165: 477: 100.00
+	Hs
		1271315 EVPL_HUMAN (2-640): 2.11e-09: 64.9: 7.68		TB22B_HUMAN (1-505): 9.73e-165: 477: 100.00
+	Hs
		1068607 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		TBCK_HUMAN (171-492): 9.73e-71: 243: 23.03
+	Hs
		1045461 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		TBCK_HUMAN (171-492): 9.73e-71: 243: 23.03
+	Hs
		164642 SPTN2_HUMAN (73-1521): 7.79e-13: 76.4: 12.03		TBCK_HUMAN (171-492): 9.73e-71: 243: 23.03
+	Hs
		963373 SPTB2_HUMAN (559-1683): 4.02e-10: 67.6: 11.36		TBCK_HUMAN (171-492): 9.73e-71: 243: 23.03